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A1593 Sigma-Aldrich

Ampicillin

meets USP testing specifications

Synonym: D-(−)-α-Aminobenzylpenicillin, Ampicillin trihydrate

  • CAS Number 7177-48-2

  • Empirical Formula (Hill Notation) C16H19N3O4S · 3H2O

  • Molecular Weight 403.45

  •  Beilstein/REAXYS Number 5399534

  •  EC Number 200-709-7

  •  MDL number MFCD00072036

  •  PubChem Substance ID 24890564

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Properties

Related Categories A - K, Analytical/Chromatography, Antibacterial, Antibiotics, Antibiotics A to Z,
InChI Key   RXDALBZNGVATNY-CWLIKTDRSA-N
form   solid
color   white
mp   198-200 °C (dec.) (lit.)
solubility   H2O: soluble 10 g/L
suitability   meets USP testing specifications
Featured Industry   Pharmaceutical (small molecule)
Mode of action   cell wall synthesis | interferes
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria
storage temp.   2-8°C

Description

General description

Chemical structure: ß-lactam

Application

Used to select for ampicillin resistance in mutated and transformed cells.

Biochem/physiol Actions

A β-lactam antibiotic with an amino group side chain attached to the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli . Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.

Packaging

25g

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
XH8425000

Documents

Certificate of Analysis

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Certificate of Origin

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Protocols & Articles

Related Content

Antibiotics Selection Guide

The Antibiotic Selection Guide enables researchers to spend more time on their research discoveries and less time seeking established antibiotic information. Link to hundreds of antibiotics for conta...
Keywords: Antibiotics, Cell biology, Cell culture, Genetic, High performance liquid chromatography, Reversed-phase chromatography

Peer-Reviewed Papers
15

References

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