EMAIL THIS PAGE TO A FRIEND
A7250 Sigma-Aldrich

N-Acetyl-L-cysteine

Sigma Grade, ≥99% (TLC), powder

Synonym: LNAC, NAC

  • CAS Number 616-91-1

  • Linear Formula HSCH2CH(NHCOCH3)CO2H

  • Molecular Weight 163.19

  •  Beilstein/REAXYS Number 1724426

  •  EC Number 210-498-3

  •  MDL number MFCD00004880

  •  PubChem Substance ID 24277970

  •  NACRES NA.26

Purchase

Properties

Related Categories Amino Acids, Amino acids, Antioxidant and Free Radical Scavengers, Application Index, Biochemicals and Reagents,
Quality Level   200
grade   Sigma Grade
assay   ≥99% (TLC)
form   powder
application(s)   cell analysis: suitable
color   white to off-white
mp   106-108 °C (lit.)
solubility   H2O: 100 mg/mL (with heating)
storage temp.   2-8°C
SMILES string   CC(=O)N[C@@H](CS)C(O)=O
InChI   1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1
InChI key   PWKSKIMOESPYIA-BYPYZUCNSA-N

Description

Application

N-Acetyl-L-cysteine has been used to suppress oxygen-dependent hydroxyurea sensitivity in Saccharomyces cerevisiae. It has also been used as an antioxidant for the treatment of C2C12 murine myoblasts.

Packaging

1 kg in poly bottle

5, 10, 25, 50, 100, 500 g in poly bottle

Biochem/physiol Actions

Antioxidant and mucolytic agent. Increases cellular pools of free radical scavengers. Reported to prevent apoptosis in neuronal cells but induce apoptosis in smooth muscle cells. Inhibits HIV replication. May serve as a substrate for microsomal glutathione transferase.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
RTECS 
HA1660000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number
Protocols & Articles

Articles

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.1 During the oxi...
Biofiles Volume 2 Article 2
Keywords: Adhesion, Anti-inflammatory agents, Applications, Cancer, Cardiovascular, Catalysis, Diabetes, Diseases, Gene expression, Metabolism, Neurodegenerative Diseases, Peroxidations, Phosphorylations, Prebiotics, Probiotics, Reductions, Transcription, Transduction, Vitamins

HPLC Analysis of 15N-Acetylcysteine Enantiomers on Astec® (R,R) P-CAP™

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of 15N-Acetylcysteine Enantiomers on Astec® (R,R) P-CAP™
Keywords: Chromatography, High performance liquid chromatography

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

08168 Timestrip Plus 8 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?