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B0770 Sigma-Aldrich

Brilliant Blue G

pure

Synonym: Acid blue 90, Coomassie Brilliant Blue G

  • CAS Number 6104-58-1

  • Empirical Formula (Hill Notation) C47H48N3NaO7S2

  • Molecular Weight 854.02

  •  Colour Index Number 42655

  •  Beilstein/REAXYS Number 5230822

  •  EC Number 228-058-4

  •  MDL number MFCD00078482

  •  PubChem Substance ID 24891535

  •  NACRES NA.47

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Properties

Related Categories B, Cell Biology, Core Bioreagents, Hematology and Histology, Life Science Reagents for Protein Electrophoresis,
Quality Level   200
InChI Key   RWVGQQGBQSJDQV-UHFFFAOYSA-M
form   powder
solubility   H2O: 1 mg/mL

Description

Application

Brilliant Blue G has been used for determining the urine protein concentration. It has been used for the protein band detection after SDS-PAGE (sodium dodecyl sulfate polyacrylamide gel electrophoresis). It has been used as a P2X7R (purinergic receptor) antagonist.

Packaging

5, 25, 100 g in glass bottle

Biochem/physiol Actions

Brilliant Blue G is used for staining protein(s) in polyacrylamide gels. It is also a P2X7 purinergic receptor antagonist. The receptor is mainly involved in neuroinflammatory events. In human SOD1G93A amyotrophic lateral sclerosis mouse, administration of brilliant blue G reduces body weight loss. However, it does not affect survival or motor coordination in transgenic mice.

P2X7 purinergic receptor antagonist.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Single- & multi-channel pipettes from BRAND
Protocols & Articles
Peer-Reviewed Papers
15

References

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