EMAIL THIS PAGE TO A FRIEND
B1000000

Betamethasone

European Pharmacopoeia (EP) Reference Standard

Synonym: 9α-Fluoro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16β-methylprednisolone

  • CAS Number 378-44-9

  • Empirical Formula (Hill Notation) C22H29FO5

  • Molecular Weight 392.46

  •  MDL number MFCD00062969

  •  PubChem Substance ID 329773150

  •  NACRES NA.24

Purchase

Properties

Related Categories Analytical Standards, Analytical/Chromatography, EP Standards, EP Standards A - B, Pharmacopeia & Metrological Institutes Standards More...
biological source   synthetic
grade   pharmaceutical primary standard
Agency/Method   EP
form   neat
packaging   pkg of 60 mg
mfr. no.   EDQM
storage condition   protect from light
color   white
mp   235-237 °C (lit.)
  235.6 °C (456.1°F at 1013.0 hPa)
solubility   water: slightly soluble 0.063 g/L at 37 °C
density   0.305 g/cm3 at 25 °C (77°F)
Featured Industry   Pharmaceutical (small molecule)
format   neat
shipped in   ambient
storage temp.   2-8°C
SMILES string   [H][C@@]12C[C@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C
InChI   1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
InChI key   UREBDLICKHMUKA-DVTGEIKXSA-N
Gene Information   human ... NR3C1(2908)

Description

General description

Betamethasone, a synthetic glucocorticoid, belongs to the corticosteroid family of active pharmaceutical ingredients (APIs).
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Betamethasone EP reference standard may be used as a pharmaceutical primary standard for the determination of the analyte in pharmaceutical formulations by chromatographic and spectrophotometric techniques.

Packaging

Unit quantity: 60 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference subtance catalogue.

Caution

Please find SDS provided by EDQM here..

Other Notes

Sales restrictions may apply.

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles

Articles

HPLC Analysis of Glucocorticoids on Ascentis® C8

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Glucocorticoids on Ascentis® C8
Keywords: Chromatography, Clinical, High performance liquid chromatography, Hormones

Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

PHR1779 Betamethasone Acetate, Pharmaceutical Secondary Standard; Certified Reference Material
PHR1398 Betamethasone, Pharmaceutical Secondary Standard; Certified Reference Material
08168 Timestrip Plus 8 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?