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BP460

Nicotinamide

British Pharmacopoeia (BP) Reference Standard

Synonym: Niacinamide, Nicotinic acid amide, Pyridine-3-carboxylic acid amide, Vitamin B3, Vitamin PP

  • CAS Number 98-92-0

  • Empirical Formula (Hill Notation) C6H6N2O

  • Molecular Weight 122.12

  •  Beilstein/REAXYS Number 383619

  •  MDL number MFCD00006395

  •  NACRES NA.24

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Properties

grade   pharmaceutical primary standard
Agency/Method   BP
mfr. no.   BP
mp   128-131 °C (lit.)
storage temp.   −20°C
SMILES string   NC(=O)c1cccnc1
InChI   1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
InChI key   DFPAKSUCGFBDDF-UHFFFAOYSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Nicotinamide, a member of the family of water-soluble B vitamins, is generally produced from nicotinic acid (vitamin B3). It is often present in food products. It has been reported to have been effective in the treatment of pellagra, psoriasis, schizophrenia, and type I diabetes. It is also shown to possess anti-inflammatory activity.

Application

Nicotinamide may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations and biological fluids by chromatography, UV-visible spectrophotometry and multivariate analysis.

Biochem/physiol Actions

Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor

Packaging

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Other Notes

Sales restrictions may apply.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
Flash Point(F) 
359.6 °F
Flash Point(C) 
182 °C

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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