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C0400000

Calcium pantothenate

European Pharmacopoeia (EP) Reference Standard

Synonym: (R)-(+)-N-(2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl)-β-alanine hemicalcium salt, D-Pantothenic acid hemicalcium salt, Calcium D-pantothenate, Vitamin B5

  • CAS Number 137-08-6

  • Linear Formula HOCH2C(CH3)2CH(OH)CONHCH2CH2CO2 ·1/2Ca

  • Molecular Weight 238.27

  •  Beilstein/REAXYS Number 3769272

  •  MDL number MFCD00002766

  •  PubChem Substance ID 329774782

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, EP Standards, EP Standards C - D, Pharmacopeia & Metrological Institutes Standards More...
biological source   synthetic
grade   pharmaceutical primary standard
Agency/Method   EP
form   neat
mfr. no.   EDQM
Featured Industry   Pharmaceutical (small molecule)
format   neat
storage temp.   2-8°C
SMILES string   CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)O[Ca]OC(=O)CCNC(=O)[C@H](O)C(C)(C)CO
InChI   1S/2C9H17NO5.Ca/c2*1-9(2,5-11)7(14)8(15)10-4-3-6(12)13;/h2*7,11,14H,3-5H2,1-2H3,(H,10,15)(H,12,13);/q;;+2/p-2/t2*7-;/m00./s1
InChI key   FAPWYRCQGJNNSJ-UBKPKTQASA-L

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Calcium pantothenate, the calcium salt of pantothenic acid, is a coenzyme A component that plays an important role in the metabolism of proteins, fats and carbohydrates. It is employed in vitamin supplements for the treatment of acne, osteoarthritis, rheumatoid arthritis, etc.

Application

Calcium pantothenate may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations by various chromatography and spectrophotometric techniques.

Precursor in the biosynthesis of coenzyme A.

Packaging

Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference subtance catalogue.

Caution

Please find SDS provided by EDQM here..

Physical properties

Due to the unstable, hygroscopic nature of the free acid, the calcium salt is employed.

Other Notes

Sales restrictions may apply.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

HPLC Analysis of B-Vitamins in Vitamin Water using Ascentis® Express RP-Amide and UV Detection

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of B-Vitamins in Vitamin Water using Ascentis® Express RP-Amide and UV Detection
Keywords: Anticonvulsants, Chromatography, Pharmaceutical, Vitamins

HPLC Analysis of B-vitamins on Ascentis® Express RP-Amide using UV detection

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of B-vitamins on Ascentis® Express RP-Amide using UV detection
Keywords: Anticonvulsants, Chromatography, Pharmaceutical, Vitamins

HPLC Analysis of Water Soluble B Vitamins on Ascentis® Express RP-Amide

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Water Soluble B Vitamins on Ascentis® Express RP-Amide
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical, Vitamins

HPLC Analysis of Water-Soluble B-Vitamins on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Water-Soluble B-Vitamins on Ascentis® Express C18
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical, Vitamins

HPLC Analysis of Water-Soluble B-Vitamins on Ascentis® Express F5

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Water-Soluble B-Vitamins on Ascentis® Express F5
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical, Vitamins

UHPLC Analysis of B Vitamins in Vitamin Water on Titan™ C18 using UV Detection

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of B Vitamins in Vitamin Water on Titan™ C18 using UV Detection
Keywords: Anticonvulsants, Chromatography, Pharmaceutical, Vitamins

UHPLC Analysis of B-vitamins on Titan™ C18 using UV detection

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of B-vitamins on Titan™ C18 using UV detection
Keywords: Anticonvulsants, Chromatography, Pharmaceutical, Vitamins

Peer-Reviewed Papers
15

References

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PHR1232 Calcium-d-pantothenate, Pharmaceutical Secondary Standard; Certified Reference Material
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