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C0430 Supelco

(−)-Cotinine solution

drug standard, 1.0 mg/mL in methanol

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Properties

Related Categories 1694 Pharmaceuticals & Personal Care Products, Additional Standards, Alkaloids, Analytical Standards, Analytical/Chromatography,
Quality Level   100
grade   drug standard
Agency/Method   EPA 1694
concentration   1.0 mg/mL in methanol
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
Featured Industry   Environmental
Pharmaceutical (small molecule)
format   single component solution
storage temp.   2-8°C
SMILES string   CN1[C@@H](CCC1=O)c2cccnc2
InChI   1S/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3/t9-/m0/s1
InChI key   UIKROCXWUNQSPJ-VIFPVBQESA-N
Gene Information   human ... CYP1A2(1544), CYP2A6(1548)
mouse ... Cyp2a5(13087)

Description

General description

(−)-Cotinine is a major metabolite of nicotine, widely used as a biochemical marker for to evaluate the exposure to environmental tobacco smoke, for the validation of abstinence smoking and to determine the percentage of active smoking behavior.

Application

(−)-Cotinine solution has been used as a standard in the analysis of nicotine in air samples using ultra performance liquid chromatography-mass spectrometry (UPLC-MS). (−)-Cotinine may be may used as an analytical reference standard for the quantification of the analyte in biological samples using high-performance liquid chromatography technique.

(−)-Cotinine solution has been used as a standard in the analysis of nicotine in air samples using ultra performance liquid chromatography-mass spectrometry (UPLC-MS).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

1 mL in ampule

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
1
Flash Point(F) 
51.8 °F
Flash Point(C) 
11 °C
Protocols & Articles
Peer-Reviewed Papers
15

References

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