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C2250000

Clindamycin hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonym: (7S)-7-Chloro-7-deoxylincomycin hydrochloride, Cleocin

  • CAS Number 21462-39-5

  • Empirical Formula (Hill Notation) C18H33ClN2O5S · HCl

  • Molecular Weight 461.44

  •  Beilstein/REAXYS Number 4070786

  •  MDL number MFCD07793327

  •  PubChem Substance ID 329774985

  •  NACRES NA.24

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Properties

Related Categories Additional Standards, Analytical Standards, Analytical/Chromatography, Chromatography, Clindamycin,
grade   pharmaceutical primary standard
form   neat
Featured Industry   Pharmaceutical (small molecule)
format   neat
SMILES string   Cl.CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@H]([C@H](C)Cl)C2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O
InChI   1S/C18H33ClN2O5S.ClH/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25);1H/t9-,10+,11-,12+,13-,14+,15+,16+,18+;/m0./s1
InChI key   AUODDLQVRAJAJM-XJQDNNTCSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

Clindamycin is a semi-synthetic, lincosamide antibiotic that is prepared from lincomycin. It inhibits bacterial protein synthesis by hydrogen bond interactions with the 23S rRNA component of the 50S ribosomal subunit thus inducing dissociation of the peptidyl-t-RNA complex. It has antibacterial activity against Gram-positive cocci and antiprotozoal activity against Taxoplasma.

Packaging

Unit quantity: 200 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference subtance catalogue.

Other Notes

Antibacterial and antiprotozoal antibiotic of the lincosamide class.

Sales restrictions may apply.

Caution

Please find SDS provided by EDQM here..

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

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Description

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PHR1021 Clindamycin Phosphate, Pharmaceutical Secondary Standard; Certified Reference Material
08168 Timestrip Plus 8 °C

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