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C9231 Sigma-Aldrich

Carbenicillin disodium

meets USP testing specifications

Synonym: α-Carboxybenzylpenicillin disodium salt, Carbenicillin disodium salt

  • CAS Number 4800-94-6

  • Empirical Formula (Hill Notation) C17H16N2Na2O6S

  • Molecular Weight 422.36

  •  Beilstein Registry Number 5722128

  •  EC Number 225-360-8

  •  MDL number MFCD00077683

  •  PubChem Substance ID 24893142

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Properties

Related Categories A - K, Analytical/Chromatography, Antibacterial, Antibiotics, Antibiotics A to Z,
InChI Key   RTYJTGSCYUUYAL-YCAHSCEMSA-L
form   solid
solubility   H2O: 50 mg/mL
suitability   meets USP testing specifications
Featured Industry   Pharmaceutical (small molecule)
Mode of action   cell wall synthesis | interferes
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria
storage temp.   2-8°C

Description

Analysis Note

Stable at 37 °C for 3 days

Application

Used for selection of ampr transformed cells. Used to study the role of penicillin-sensitive transpeptidases in cell wall biosynthesis.

Biochem/physiol Actions

Carboxypenicillin antibiotic that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Analog to ampicillin.
Antimicrobial spectrum: Gram-positive and Gram-negative bacteria, Pseudomonas.

General description

Chemical structure: ß-lactam

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
ON9105000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

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The Antibiotic Selection Guide enables researchers to spend more time on their research discoveries and less time seeking established antibiotic information. Link to hundreds of antibiotics for conta...
Keywords: Antibiotics, Cell biology, Cell culture, Genetic, High performance liquid chromatography, Reversed-phase chromatography

Peer-Reviewed Papers
15

References

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