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D0710000

Dexamethasone acetate

European Pharmacopoeia (EP) Reference Standard

Synonym: 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione-21-acetate, 9α-Fluoro-16α-methylprednisolone-21-acetate, Dexamethasone 21-acetate, Prednisolone F acetate

  • CAS Number 1177-87-3

  • Empirical Formula (Hill Notation) C24H31FO6

  • Molecular Weight 434.50

  •  Beilstein/REAXYS Number 2342608

  •  MDL number MFCD00027407

  •  PubChem Substance ID 329798629

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, EP Standards, EP Standards C - D, Pharmacopeia & Metrological Institutes Standards More...
biological source   synthetic
grade   pharmaceutical primary standard
Agency/Method   EP
form   neat
packaging   pkg of 150 mg
mfr. no.   EDQM
storage condition   protect from light
color   white
solubility   water: <0.1 g/L
Featured Industry   Pharmaceutical (small molecule)
format   neat
shipped in   ambient
storage temp.   2-8°C
SMILES string   [H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@@H](C)[C@]4(O)C(=O)COC(C)=O
InChI   1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1
InChI key   AKUJBENLRBOFTD-RPRRAYFGSA-N
Gene Information   human ... NR3C1(2908)

Description

General description

Dexamethasone acetate (Decadron-LA) belongs to the class of long-acting glucocorticoids, commonly used as a pharmaceutical ingredient in creams, ointments, microemulsions, lotions, aerosols, etc.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Dexamethasone acetate is used as a pharmaceutical primary standard to quantify the analyte in pharmaceutical formulations using chromatography ttechniques.

Packaging

Unit quantity: 150 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference subtance catalogue.

Caution

Please find SDS provided by EDQM here..

Other Notes

Sales restrictions may apply.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

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08168 Timestrip Plus 8 °C
PHR1527 Dexamethasone Acetate, Pharmaceutical Secondary Standard; Certified Reference Material

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