E3764 Sigma-Aldrich


analytical standard

Synonym: 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid



Biochem/physiol Actions

Hydrophilic fluorquinolone antibiotic. Substrate of NorA, an energy dependent drug efflux pump in Staphylococcus aureus. Expression of NorA is responsible for some drug resistant infections.


Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Chemical structure: fluoroquinolone

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. E3764.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit

Price and Availability

Expore Enzymes, Proteins & Cofactors

Milli-Q® Water Purification Solutions

Biomedical Applications
Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 


Certificate of Analysis

Certificate of Origin

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option:
How do I find price and availability?
There are several ways to find pricing and availability for our products.  Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers. 
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
In what solvent can Product E3764, Enoxacin, be reconstituted?
This product may be reconstituted in DMSO at 8 mg/mL.
What class of antibiotics does Product E3764, Enoxacin, belong to?
Enoxacin is a broad spectrum fluoroquinolone antibiotic used in the treatment of urinary tract infections.  
What working concentration has been reported for Product E3764, Enoxacin?
Enoxacin has been used at 1 mM on cultured Calu-3 cells to inhibit transepithelial transport of ciprofloxacin, as reported in Antimicrob. Agents Chemother. 41(12), 2693-2698 (1997).
My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
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Peer-Reviewed Papers


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