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F0175000 Sigma-Aldrich

Flucytosine

European Pharmacopoeia (EP) Reference Standard

Synonym: 4-amino-5-fluoro-2(1H)-pyrimidinone, 5-Fluorocytosine, Flucytosine

  • CAS Number 2022-85-7

  • Empirical Formula (Hill Notation) C4H4FN3O

  • Molecular Weight 129.09

  •  Beilstein/REAXYS Number 127285

  •  MDL number MFCD00006035

  •  PubChem Substance ID 329799634

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, EP Standards, EP Standards E - F, Pharmacopeia & Metrological Institutes Standards More...
InChI Key   XRECTZIEBJDKEO-UHFFFAOYSA-N
form   neat
mp   298-300 °C (dec.) (lit.)
Featured Industry   Pharmaceutical (small molecule)
format   neat

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

Nucleoside analog that has antifungal activities. 5-FC is deaminated by cytosine deaminase to product 5-fluorouracil, resulting in RNA miscoding. 5-Fluorocytosine inhibits DNA and RNA synthesis and interferes with ribosomal protein synthesis.

Packaging

Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference subtance catalogue.

Caution

Please find SDS provided by EDQM here..

Other Notes

Sales restrictions may apply.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

HPLC Analysis of Fluorinated Pyrimidine Nucleosides on Ascentis® RP-Amide

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Fluorinated Pyrimidine Nucleosides on Ascentis® RP-Amide
Keywords: Chromatography, Clinical, High performance liquid chromatography

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08168 Timestrip Plus 8 °C
PHR1659 Flucytosine, Pharmaceutical Secondary Standard; Certified Reference Material

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