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F8798 Sigma-Aldrich

Folic acid

meets USP testing specifications

Synonym: PteGlu, Pteroyl-L-glutamic acid, Vitamin M

  • CAS Number 59-30-3

  • Empirical Formula (Hill Notation) C19H19N7O6

  • Molecular Weight 441.40

  •  Beilstein/REAXYS Number 100781

  •  EC Number 200-419-0

  •  MDL number MFCD00079305

  •  eCl@ss 34058014

  •  PubChem Substance ID 24894977

  •  NACRES NA.21

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Properties

Related Categories Acids, Acids & Bases, Analytical/Chromatography, Biochemicals and Reagents, Chemical Synthesis,
Quality Level   200
biological source   synthetic (organic)
assay   97.0-102.0% dry basis
form   solid
application(s)   cell analysis: suitable
color   yellow
mp   > 285 °C
suitability   meets USP testing specifications
Featured Industry   Pharmaceutical (small molecule)
SMILES string   NC1=NC(=O)c2nc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cnc2N1
InChI   1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1
InChI key   OVBPIULPVIDEAO-LBPRGKRZSA-N

Description

General description

Folic acid, also known as pteroyl-L-glutamic acid, belongs to the vitamin B group. The conformational analysis of folic acid in the solution has been reported based on nuclear magnetic resonance (NMR) and theoretical calculations. The reaction kinetics of the photodecomposition under ultraviolet radiation has been investigated. This product is a high quality pharmacopoeia product that meets the testing specifications of USP (United States Pharmacopoeia). It can be employed in research and pilot studies.

Application

Folic acid has been used in a study to investigate its protective effects against the toxicity caused by valproic acid (VPA) on maternal liver tissue. It has also been used as standard for the quantification of plasma folic acid by reversed-phase HPLC.

Packaging

5, 25, 100 g in poly bottle

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

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Importance and uses of folic acid in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures
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Peer-Reviewed Papers
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References

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