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G2164 Sigma-Aldrich

Gluconolactone

meets USP testing specifications

Synonym: δ-Gluconolactone, 1,2,3,4,5-Pentahydroxycaproic acid δ-lactone, D-(+)-Gluconic acid δ-lactone, D-(+)-Dextronic acid δ-lactone

  • CAS Number 90-80-2

  • Empirical Formula (Hill Notation) C6H10O6

  • Molecular Weight 178.14

  •  Beilstein/REAXYS Number 83286

  •  EC Number 202-016-5

  •  MDL number MFCD00006647

  •  PubChem Substance ID 24895089

  •  NACRES NA.21

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Properties

Related Categories Analytical/Chromatography, Carbohydrates, Core Bioreagents, Pharmacopoeia, Pharmacopoeia A-Z,
Quality Level   200
mp   160 °C (dec.) (lit.)
suitability   meets USP testing specifications
Featured Industry   Pharmaceutical (small molecule)
SMILES string   OC[C@H]1OC(=O)[C@H](O)[C@@H](O)[C@@H]1O
InChI   1S/C6H10O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-5,7-10H,1H2/t2-,3-,4+,5-/m1/s1
InChI key   PHOQVHQSTUBQQK-SQOUGZDYSA-N

Description

General description

Gluconolactone is a non-toxic component of the skin. It has anti-oxidant and free radical scavenging effects. Gluconolactone has antiaging and skin-firming properties. It acts as a β-glucosidase inhibitor. Gluconolactone stimulates cellulase gene expression.

Application

Gluconolactone has been used:
• to control the acidification kinetics of natural rubber latex (NRL) suspensions
• to study its effects on inhibition and disintegration of collagen fibrils
• to prepare alginate hydrogel

Packaging

1 kg in poly bottle

100 g in poly bottle

Biochem/physiol Actions

Glucono-d-lactone increased the doubling time and activated enzymes involved in the oxidative pentose phosphate pathway of Saccharomyces cerevisiae.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
LZ5184000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Single- & multi-channel pipettes from BRAND
Protocols & Articles
Peer-Reviewed Papers
15

References

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