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H3393 Sigma-Aldrich

Heparin sodium salt from porcine intestinal mucosa

Grade I-A, ≥180 USP units/mg

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Description

Packaging

10000, 25000, 50000, 100000, 250000, 500000, 1000000 units in poly bottle

Application

Heparin sodium salt from porcine intestinal mucosa has been supplemented in the medium prepared for insemination of oocytes with spermatozoa. It has been used to check the effect of heparin on FGF21 (fibroblast growth factor 21) signaling.

Biochem/physiol Actions

Heparin is mainly responsible for the delay in the coagulation of blood. It enhances the antithrombin-mediated inactivation of proteases in the coagulation pathway.

Recommended products

Elite grade heparin for diagnostic manufacturing is available as product number SRE0027

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
MI0850000

Frequently Asked Questions

What is the molecular weight of Heparin sodium salt?
Heparin is a mixture of polyanion chains having molecular weights ranging from 6,000 to 30,000 Daltons, with most chains in the range of 17,000 to 19,000 Daltons.
How muchHeparin sodium salt, is used to prevent coagulation?
We suggest using 20 to 50 units per mL of blood.
What is the best way to sterilize Heparin sodium salt?
Although solutions may be autoclaved at 121 °C for 5 to 10 minutes, we generally recommend sterile filtration. This is because prolonged autoclaving may have an effect on its activity.
What concentration of Heparin sodium salt,can I use to inhibit RNAse activity?
Heparin has been used at concentrations ranging from 100 to 500 μg/mL. This has been reported in the J. Biol. Chem., 248, 2095 (1973).
Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How do I find price and availability?
There are several ways to find pricing and availability for our products.Once you log onto our website, you will find the price and availability displayed on the product detail page.You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 orview local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
My question is not addressed here, how can I contact Technical Service for assistance?
Ask a Scientist here.
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References

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H3149 Heparin sodium salt from porcine intestinal mucosa, Grade I-A, ≥180 USP units/mg, powder, BioReagent, suitable for cell culture

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