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H6878 Sigma-Aldrich

8-Hydroxyquinoline

crystalline

Synonym: 8-Hydroxyquinoline, 8-Oxychinolin, 8-Quinolinol, Oxine

  • CAS Number 148-24-3

  • Empirical Formula (Hill Notation) C9H7NO

  • Molecular Weight 145.16

  •  Beilstein/REAXYS Number 114512

  •  EC Number 205-711-1

  •  MDL number MFCD00006807

  •  PubChem Substance ID 24895771

  •  NACRES NA.21

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Properties

Related Categories A - K, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics G-M,
Quality Level   200
assay   98.5-101.5%
form   crystalline
bp   267 °C/752 mmHg (lit.)
mp   70-73 °C (lit.)
Mode of action   DNA synthesis | interferes
  enzyme | inhibits
antibiotic activity spectrum   fungi
SMILES string   Oc1cccc2cccnc12
InChI   1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H
InChI key   MCJGNVYPOGVAJF-UHFFFAOYSA-N

Description

General description

Chemical structure: quinolone

Packaging

25, 100, 500 g in glass bottle

Application

Used as a lipophilic monoprotic bidentate chelating agent.

Biochem/physiol Actions

RNA synthesis inhibitor that acts as a fungicide against Trichophyton mentagrophytes, Myrothecium verrucaria, and Trichoderma viride. The antifungal mechanism of action is not clear but appears to be structurally related.

Safety & Documentation

Safety Information

Signal word 
Danger
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
VC4200000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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