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I0100000 Sigma-Aldrich

Imipramine hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonym: 10,11-Dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine hydrochloride, 5-[3-(Dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride

  • CAS Number 113-52-0

  • Empirical Formula (Hill Notation) C19H24N2 · HCl

  • Molecular Weight 316.87

  •  MDL number MFCD00012669

  •  PubChem Substance ID 329815297

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, EP Standards, EP Standards I - K, Pharmacopeia & Metrological Institutes Standards More...
InChI Key   XZZXIYZZBJDEEP-UHFFFAOYSA-N
form   neat
Featured Industry   Pharmaceutical (small molecule)
format   neat

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

Tricyclic antidepressant; inhibits the serotonin and norepinephrine transporters with Kis of 7.7 nM and 67 nM, respectively. Has little effect on the dopamine transporter (Ki = 25 μM).

Packaging

Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference subtance catalogue.

Caution

Please find SDS provided by EDQM here..

Other Notes

Sales restrictions may apply.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis

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Protocols & Articles

Articles

UHPLC Analysis of Desipramine and Imipramine on Titan™ C18

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of Desipramine and Imipramine on Titan™ C18
Keywords: Chromatography, Mass spectrometry, Pharmaceutical

UHPLC/MS/MS Analysis of 25 Small Molecule Pharmaceutical Compounds on Ascentis® Express RP-Amide

From our library of Articles, Sigma-Aldrich presents UHPLC/MS/MS Analysis of 25 Small Molecule Pharmaceutical Compounds on Ascentis® Express RP-Amide
Keywords: Chromatography, High performance liquid chromatography, Mass spectrometry, Pharmaceutical, Separation

Peer-Reviewed Papers
15

References

Related Products

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Description

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PHR1797 Imipramine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material
08168 Timestrip Plus 8 °C

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