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L5750 Sigma-Aldrich

Sodium dodecyl sulfate

92.5-100.5% based on total alkyl sulfate content basis

Synonym: Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate

  • CAS Number 151-21-3

  • Linear Formula CH3(CH2)11OSO3Na

  • Molecular Weight 288.38

  •  Beilstein/REAXYS Number 3599286

  •  EC Number 205-788-1

  •  MDL number MFCD00036175

  •  eCl@ss 39093306

  •  PubChem Substance ID 24896412

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Properties

Related Categories Alkyl Sulfates, Anionic Detergents, Antigen-Vaccine Preparation, Biochemicals and Reagents, Cell Culture,
description   anionic
InChI Key   DBMJMQXJHONAFJ-UHFFFAOYSA-M
assay   92.5-100.5% based on total alkyl sulfate content basis
mol wt   288.38 g/mol
aggregation number   62
CMC   7-10 mM (20-25°C)
mp   204-207 °C (lit.)
transition temp   cloud point >100 °C
solubility   water: soluble
HLB   40

Description

Application

Sodium dodecyl sulfate has been used:
• to dissolve insoluble purple formazan in 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay
• to perform SDS–PAGE of yeast tubulin
• as an additive in linolenic acid solution to assess the total antioxidative activity (TAA) of the bacteria using the linolenic acid test (LA-test)

Anionic detergent

Packaging

1 kg in poly bottle

100, 500 g in poly bottle

5 kg in poly drum

Biochem/physiol Actions

Sodium dodecyl sulfate (SDS)/lauryl sulfate, an ionic detergent has the ability to distract biological membranes. It can block RNase and deoxyribonuclease (DNase) activity. SDS is one of the main constituents of several reagents, that are used to purify nucleic acids. It is also considered as a permeability enhancer in oral formulations.

Quality

Predominantly (approx. 70%) C12; lauryl sulfate, sodium salt; balance consists of higher homologs.

Analysis Note

Actual composition given on label

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Precautionary statements 
RIDADR 
UN1325 - class 4.1 - PG 3 - Flammable solids, organic, n.o.s., HI: all
WGK Germany 
2
RTECS 
WT1050000
Flash Point(F) 
338 °F
Flash Point(C) 
170 °C

Documents

Certificate of Analysis

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Certificate of Origin

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Single- & multi-channel pipettes from BRAND
Protocols & Articles
Peer-Reviewed Papers
15

References

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