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M8277 Supelco

Midodrine hydrochloride

analytical standard, for drug analysis

Synonym: (±)-1-(2,5-Dimethoxyphenyl)-2-glycinamidoethanol

  • CAS Number 3092-17-9

  • Empirical Formula (Hill Notation) C12H18N2O4 · HCl

  • Molecular Weight 290.74

  •  MDL number MFCD00079455

  •  PubChem Substance ID 329818055

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Properties

Related Categories Additional Standards, Analytical Standards, Analytical/Chromatography, Cardiac Drugs, Chemical Structure,
Quality Level   100
grade   analytical standard, for drug analysis
form   neat
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
Featured Industry   Forensics and Toxicology
Pharmaceutical (small molecule)
Veterinary
format   neat
SMILES string   Cl.COc1ccc(OC)c(c1)C(O)CNC(=O)CN
InChI   1S/C12H18N2O4.ClH/c1-17-8-3-4-11(18-2)9(5-8)10(15)7-14-12(16)6-13;/h3-5,10,15H,6-7,13H2,1-2H3,(H,14,16);1H
InChI key   MGCQZNBCJBRZDT-UHFFFAOYSA-N
Gene Information   human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

Description

General description

Midodrine is a prodrug and a long acting α-adrenergic stimulating agent, and forms an active metabolite, desglymidodrine, which causes an elevation of the systemic blood pressure with the reduction in heart rate.

Application

Midodrine hydrochloride may be used as an analytical reference standard for the quantification of the analyte in biological samples and pharmaceutical formulations using different chromatography techniques.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

α-Adrenergic agonist; vasoconstrictor

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
WGK 3
RTECS 
AB4343000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

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