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M9546 Sigma-Aldrich

D-Mannitol

BioXtra, ≥98% (HPLC)

Synonym: Mannite

  • CAS Number 69-65-8

  • Empirical Formula (Hill Notation) C6H14O6

  • Molecular Weight 182.17

  •  Beilstein Registry Number 1721898

  •  EC Number 200-711-8

  •  MDL number MFCD00064287

  •  PubChem Substance ID 24897341

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Properties

Related Categories Biochemicals and Reagents, Carbohydrates, Carbohydrates A to Z, Carbohydrates M-O, Cell Biology,
InChI Key   FBPFZTCFMRRESA-KVTDHHQDSA-N
product line   BioXtra
assay   ≥98% (HPLC)
impurities   ≤0.0005% Phosphorus (P)
  ≤0.01% Insoluble matter
ign. residue   ≤0.01%
mp   167-170 °C (lit.)
solubility   H2O: 1 M, clear, colorless
anion traces   chloride (Cl-): ≤0.05%
  sulfate (SO42-): ≤0.05%
cation traces   Al: ≤0.0005%
  Ca: ≤0.0005%
  Cu: ≤0.0005%
  Fe: ≤0.0005%
  K: ≤0.005%
  Mg: ≤0.0005%
  NH4+: ≤0.05%
  Na: ≤0.005%
  Pb: ≤0.001%
  Zn: ≤0.0005%

Description

Biochem/physiol Actions

A sugar alcohol sweet tastant. Used in sweetness inhibition studies.

D-Mannitol is used as an osmotic agent for the treatment of brain swellings.

Packaging

1 kg in poly bottle

250 g in poly bottle

Application

D-Mannitol has been used:
• as a hydroxyl radical inhibitor, to detect the hydroxyl radical generation during the reactive oxygen species (ROS) modification of chromatin
• in [3H]-mannitol permeability assay and also as a component in buffer B for measuring the transmonolayer dilution potentials
• as a component in extracellular recording solution for whole cell patch clamp recordings

General description

D-Mannitol is the alcohol form of mannose. Its molar mass is 182 g/mol. Mannitol is present widely in plants, fungi and algae. It is extracted mainly from seaweeds. It is used in food for diabetic patients as it is absorbed slowly. It is commonly used as a stabilizer, humectant, nutritive sweetener and bulking agent in food.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. M9546.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
OP2060000

Documents

Certificate of Analysis

Certificate of Origin


Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

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