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M9546 Sigma-Aldrich

D-Mannitol

BioXtra, ≥98% (HPLC)

Synonym: Mannite

  • CAS Number 69-65-8

  • Empirical Formula (Hill Notation) C6H14O6

  • Molecular Weight 182.17

  •  Beilstein/REAXYS Number 1721898

  •  EC Number 200-711-8

  •  MDL number MFCD00064287

  •  PubChem Substance ID 24897341

  •  NACRES NA.21

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Properties

Related Categories Biochemicals and Reagents, Carbohydrates, Carbohydrates A to Z, Carbohydrates M-O, Cell Biology,
Quality Level   200
product line   BioXtra
assay   ≥98% (HPLC)
impurities   ≤0.0005% Phosphorus (P)
  ≤0.01% Insoluble matter
ign. residue   ≤0.01%
mp   167-170 °C (lit.)
solubility   H2O: 1 M, clear, colorless
anion traces   chloride (Cl-): ≤0.05%
  sulfate (SO42-): ≤0.05%
cation traces   Al: ≤0.0005%
  Ca: ≤0.0005%
  Cu: ≤0.0005%
  Fe: ≤0.0005%
  K: ≤0.005%
  Mg: ≤0.0005%
  NH4+: ≤0.05%
  Na: ≤0.005%
  Pb: ≤0.001%
  Zn: ≤0.0005%
SMILES string   OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
InChI   1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
InChI key   FBPFZTCFMRRESA-KVTDHHQDSA-N

Description

General description

D-Mannitol is the alcohol form of mannose. Its molar mass is 182 g/mol. Mannitol is present widely in plants, fungi and algae. It is extracted mainly from seaweeds. It is used in food for diabetic patients as it is absorbed slowly. It is commonly used as a stabilizer, humectant, nutritive sweetener and bulking agent in food.

Application

D-Mannitol has been used:
• as a hydroxyl radical inhibitor, to detect the hydroxyl radical generation during the reactive oxygen species (ROS) modification of chromatin
• in [3H]-mannitol permeability assay and also as a component in buffer B for measuring the transmonolayer dilution potentials
• as a component in extracellular recording solution for whole cell patch clamp recordings

Packaging

1 kg in poly bottle

250 g in poly bottle

Biochem/physiol Actions

D-Mannitol is used as an osmotic agent for the treatment of brain swellings.

A sugar alcohol sweet tastant. Used in sweetness inhibition studies.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. M9546.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
RTECS 
OP2060000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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