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N1230000

Norfloxacin

European Pharmacopoeia (EP) Reference Standard

Synonym: 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid, 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino-3-quinolinecarboxylic acid

  • CAS Number 70458-96-7

  • Empirical Formula (Hill Notation) C16H18FN3O3

  • Molecular Weight 319.33

  •  MDL number MFCD00079532

  •  PubChem Substance ID 329818530

  •  NACRES NA.24

Purchase

Properties

Related Categories Analytical Standards, Analytical/Chromatography, EP Standards, EP Standards N - O, Pharmacopeia & Metrological Institutes Standards More...
grade   pharmaceutical primary standard
form   neat
mfr. no.   EDQM
Featured Industry   Pharmaceutical (small molecule)
format   neat
SMILES string   CCN1C=C(C(O)=O)C(=O)c2cc(F)c(cc12)N3CCNCC3
InChI   1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)
InChI key   OGJPXUAPXNRGGI-UHFFFAOYSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

Norfloxacin blocks DNA replication by interfering with an ATP-induced structural transition of DNA complexed with DNA gyrase (topoisomerase).
Mode of action: inhibits bacterial DNA replication
Antimicrobial spectrum: Gram-negative bacteria; less effective against Gram-positive bacteria

Packaging

Unit quantity: 20 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Caution

Please find SDS provided by EDQM here..

Other Notes

Sales restrictions may apply.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

HPLC Analysis of Antibacterials/Antifungals on Ascentis® RP-Amide, Phosphate Mobile Phase

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Antibacterials/Antifungals on Ascentis® RP-Amide, Phosphate Mobile Phase
Keywords: Antibiotics, Antifungals, Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Fluoroquinolone Antibiotics on Ascentis® Phenyl

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Fluoroquinolone Antibiotics on Ascentis® Phenyl
Keywords: Antibiotics, Chromatography, High performance liquid chromatography, Mass spectrometry, Pharmaceutical

Peer-Reviewed Papers
15

References

Related Products

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PHR1614 Norfloxacin, Pharmaceutical Secondary Standard; Certified Reference Material
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