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N5535 Sigma-Aldrich

Niacinamide

meets USP testing specifications

Synonym: Niacinamide, Nicotinamide, Nicotinic acid amide, Pyridine-3-carboxylic acid amide, Vitamin B3, Vitamin PP

  • CAS Number 98-92-0

  • Empirical Formula (Hill Notation) C6H6N2O

  • Molecular Weight 122.12

  •  Beilstein/REAXYS Number 383619

  •  EC Number 202-713-4

  •  MDL number MFCD00006395

  •  PubChem Substance ID 24897740

  •  NACRES NA.21

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Properties

Related Categories Analytical/Chromatography, Biochemicals and Reagents, Core Bioreagents, Pharmacopoeia, Pharmacopoeia A-Z,
Quality Level   200
biological source   synthetic (organic)
assay   98.5-101.5% dry basis
color   white
mp   128-131 °C (lit.)
suitability   meets USP testing specifications
Featured Industry   Pharmaceutical (small molecule)
SMILES string   NC(=O)c1cccnc1
InChI   1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
InChI key   DFPAKSUCGFBDDF-UHFFFAOYSA-N
Gene Information   human ... PARP1(142), SIRT2(22933)

Description

General description

Niacinamide, also known as 3-pyridinecarboxamide, is a water soluble vitamin. It is widely present in plants, animal food and cosmetics.

Application

Niacinamide has been used:
• as a component of islet maturation culture media
• to induce differentiation of insulin secreting cells
• to compare its preclinical effectiveness with that of progesterone

Packaging

100 g in poly bottle

Biochem/physiol Actions

Niacinamide is a primary precursor of nicotinamide adenine dinucleotide (NAD+), which is an important coenzyme in adenosine triphosphate (ATP) production. Nicotinamide deficiency is associated with pellagra.

Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
RTECS 
QS3675000
Flash Point(F) 
359.6 °F
Flash Point(C) 
182 °C

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Single- & multi-channel pipettes from BRAND
Protocols & Articles
Peer-Reviewed Papers
15

References

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