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N6160 Sigma-Aldrich

Novobiocin sodium

meets USP testing specifications

Synonym: Novobiocin sodium salt

  • CAS Number 1476-53-5

  • Empirical Formula (Hill Notation) C31H35N2NaO11

  • Molecular Weight 634.61

  •  Beilstein Registry Number 3892910

  •  EC Number 216-023-6

  •  PubChem Substance ID 24897774

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Properties

Related Categories Analytical/Chromatography, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics N-S,
suitability   meets USP testing specifications
Featured Industry   Pharmaceutical (small molecule)
Mode of action   DNA synthesis | interferes
  enzyme | inhibits
antibiotic activity spectrum   Gram-positive bacteria
storage temp.   2-8°C

Description

Application

For the production of positively supercoiled plasmid DNA. Inhibitor of bacterial DNA gyrase and eukaryotic DNA topoisomerase. Inhibitor of retrovirus RNA-dependent DNA-polymerase.

Biochem/physiol Actions

Mode of Action: Inhibits DNA synthesis by inhibiting the enzyme Topoisomerase II.
Antimicrobial spectrum: Gram-positive bacterial.

Packaging

1, 5, 25 g in glass bottle

General description

Chemical structure: coumarin-glycoside

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
RD5425000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

ISO 6579-1 for Salmonella Detection in the Food Chain

The International Organization for Standardization (ISO) published the new EN ISO 6579-1 standard in 2017, which specifies a horizontal method for the detection of Salmonella spp. in the food product...
Keywords: Culture media, Environmental, Microbiology

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Antibiotics Selection Guide

The Antibiotic Selection Guide enables researchers to spend more time on their research discoveries and less time seeking established antibiotic information. Link to hundreds of antibiotics for conta...
Keywords: Antibiotics, Cell biology, Cell culture, Genetic, High performance liquid chromatography, Reversed-phase chromatography

Peer-Reviewed Papers
15

References

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