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P4722 Sigma-Aldrich

Pyridoxine hydrochloride

meets USP testing specifications

Synonym: Adermine hydrochloride, PN HCl, Pyridoxol hydrochloride, Vitamin B6 hydrochloride

  • CAS Number 58-56-0

  • Empirical Formula (Hill Notation) C8H11NO3 · HCl

  • Molecular Weight 205.64

  •  Beilstein/REAXYS Number 3632435

  •  EC Number 200-386-2

  •  MDL number MFCD00012807

  •  eCl@ss 34058008

  •  PubChem Substance ID 24898493

  •  NACRES NA.21

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Properties

Related Categories Analytical/Chromatography, Biochemicals and Reagents, Core Bioreagents, Pharmacopoeia, Pharmacopoeia A-Z,
Quality Level   200
biological source   synthetic (organic)
assay   98.0-102.0% dry basis
form   powder
color   white
mp   214-215 °C (lit.)
suitability   meets USP testing specifications
Featured Industry   Pharmaceutical (small molecule)
SMILES string   Cl[H].Cc1ncc(CO)c(CO)c1O
InChI   1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H
InChI key   ZUFQODAHGAHPFQ-UHFFFAOYSA-N

Description

General description

Vitamin B group is water-soluble and exists in six forms namely the pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phosphate, pyridoxine 5′-phosphate and pyridoxal 5′-phosphate. The food sources of vitamin B6 include grains, nuts, fruits, vegetables and meat.

Application

Pyridoxine hydrochloride has been used to test its neuroprotective functionality in traumatic brain injury (TBI) rats. It has also been used as a reference standard to quantify vitamin B6 in feed and digesta samples using high-performance liquid chromatography(HPLC).

Packaging

10, 100 g in poly bottle

Biochem/physiol Actions

Pyridoxine plays a key role in metabolism both carbohydrates and amino acids. It supports brain development and its deficiency levels may lead to depletion of γ-aminobutyric acid (GABA) levels. Pyridoxine catalyzes the neurotransmitter biosynthesis like dopamine and serotonin. Pyridoxine in excess or deficient may lead to neuropathy.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Single- & multi-channel pipettes from BRAND
Protocols & Articles

Related Content

Vitamin B6, Pyridoxal and Pyridoxine, in Cell Culture

Importance and uses of the B6 vitamins, pyridoxal and pyridoxine, in serum-free eukaryotic, including hybridoma and Chinese Hamster Ovary (CHO) cell, cultures
Keywords: Catalysis, Cell culture, Culture media, Decarboxylations, Degradations, Eliminations, Metabolism, Neurotransmitters, Racemizations, Transaminations, Vitamins

Peer-Reviewed Papers
15

References

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