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P7045 Supelco

Phenformin hydrochloride

analytical standard

Synonym: N-(2-Phenylethyl)imidodicarbonimidic diamide monohydrochloride, Phenethylbiguanide

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Properties

Related Categories Additional Drugs, Aerobic Glycolysis (the Warburg Effect), Analytical Standards, Analytical/Chromatography, Cancer Metabolism,
Quality Level   100
grade   analytical standard
form   neat
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
Featured Industry   Pharmaceutical (small molecule)
format   neat
SMILES string   Cl.NC(=N)NC(=N)NCCc1ccccc1
InChI   1S/C10H15N5.ClH/c11-9(12)15-10(13)14-7-6-8-4-2-1-3-5-8;/h1-5H,6-7H2,(H6,11,12,13,14,15);1H
InChI key   YSUCWSWKRIOILX-UHFFFAOYSA-N

Description

General description

Phenformin hydrochloride is a biguanide derivative that shows anti-diabetic activity.

Application

Phenformin hydrochloride has been used as a test compound to study the antineoplastic activity it can exhibit in suppressing the growth of ovarian cancer cells and also human hepatocellular carcinoma cells.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

1, 10 g in glass bottle

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
DU2200000

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Oncogenes and Tumor Suppressors Reprogram Metabolism

Proliferating cells require the biosynthesis of structural components for biomass production and for genomic replication. This requires a reprogramming of the metabolic pathways to ensure nutrients s...
BioFiles v7 n4
Keywords: Aerobic, Antitumor agents, Apoptosis, Cancer, Citric Acid Cycle, Degradations, Environmental, Gene expression, Glycolysis, Growth factors, Metabolic Pathways, Metabolism, Metabolites, Nucleotide Synthesis, Pentose phosphate pathway, Phosphorylations

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

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