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PHL89591 Sigma-Aldrich

Caffeine

phyproof® Reference Substance

Synonym: 1,3,7-Trimethylxanthine

  • CAS Number 58-08-2

  • Empirical Formula (Hill Notation) C8H10N4O2

  • Molecular Weight 194.19

  •  Beilstein/REAXYS Number 17705

  •  EC Number 200-362-1

  •  MDL number MFCD00005758

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Properties

Related Categories A - D, Alkaloids / Nitrogen Containing Compounds, Alphabetical Index of Phytochemical Standards, Analytical Standards, Analytical/Chromatography,
InChI Key   RYYVLZVUVIJVGH-UHFFFAOYSA-N
product line   phyproof® Reference Substance
assay   ≥98.0% (HPLC)
mp   234-236.5 °C (lit.)
Featured Industry   Food and Beverages

Description

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

A central nervous system stimulant believed to act through adenosine receptors and monoamine neurotransmitters. It is an adenosine receptor antagonist and adenosine 3′,5′-cyclic monophosphate (cAMP) phosphodiesterase inhibitor. Thus, levels of cAMP increase in cells following treatment with caffeine. It has been reported to affect cellular calcium levels, releasing calcium from intracellular stores. It overrides the cell cycle effects of various chemicals such as protease inhibitors, preventing apoptosis; and it has been shown to inhibit cellular DNA repair mechanisms.

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
RTECS 
EV6475000

Documents

Certificate of Analysis

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Protocols & Articles
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