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PHR1005 Supelco

Acetaminophen

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: 4′-Hydroxyacetanilide, 4-Acetamidophenol, N-(4-Hydroxyphenyl)acetamide, N-Acetyl-4-aminophenol, APAP, Paracetamol

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Properties

Related Categories A-C, Acetaminophen / Paracetamol, Additional Standards, Analytical Standards, Analytical/Chromatography,
grade   certified reference material
  pharmaceutical secondary standard
InChI Key   RZVAJINKPMORJF-UHFFFAOYSA-N
form   neat
mp   168-172 °C (lit.)
Featured Industry   Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to BP 371
  traceable to PhEur P030000
  traceable to USP 1003009

Description

General description

Acetaminophen is a drug, which possesses pharmacological properties like antipyretic and analgesic property.

Application

Acetaminophen may be used as a standard in the determination of acetaminophen in human serum or plasma samples using spectrophotometric technique. It may also be used as a standard in the estimation of acetaminophen in pharmaceutical formulations using high performance liquid chromatography (HPLC).

Analgesic.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB7782 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
1

Documents

Certificate of Analysis

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Protocols & Articles

Articles

HPLC Analysis of Acetaminophen, Caffeine, Chlorpheniramine, Ibuprofen, Naproxen, Phenylephrine, and Pseudoephedrine on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Acetaminophen, Caffeine, Chlorpheniramine, Ibuprofen, Naproxen, Phenylephrine, and Pseudoephedrine on Ascentis® Express C18
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical, Separation

HPLC Analysis of Analgesics on Ascentis® C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Analgesics on Ascentis® C18
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Analgesics on Discovery® HS F5

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Analgesics on Discovery® HS F5
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Analgesics on Discovery® RP-Amide C16

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Analgesics on Discovery® RP-Amide C16
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Antitussive/Antihistamine/Antipyretic Mix on Discovery® RP-Amide C16

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Antitussive/Antihistamine/Antipyretic Mix on Discovery® RP-Amide C16
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Cold Remedy Components on Ascentis® Express 2.0 μm RP-Amide

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Cold Remedy Components on Ascentis® Express 2.0 μm RP-Amide
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical, Separation

HPLC Analysis of Pain Relievers on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Pain Relievers on Ascentis® Express C18
Keywords: Analgesics, Chromatography, Clinical, High performance liquid chromatography

Peer-Reviewed Papers
15

References

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