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PHR1036 Supelco

Pyridoxine hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: Adermine hydrochloride, PN HCl, Pyridoxol hydrochloride, Vitamin B6 hydrochloride

  • CAS Number 58-56-0

  • Empirical Formula (Hill Notation) C8H11NO3 · HCl

  • Molecular Weight 205.64

  •  Beilstein/REAXYS Number 3632435

  •  EC Number 200-386-2

  •  MDL number MFCD00012807

  •  PubChem Substance ID 329823066

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, P-S, Pharmaceutical Secondary Standards, Pharmacopeia & Metrological Institutes Standards More...
grade   certified reference material
  pharmaceutical secondary standard
InChI Key   ZUFQODAHGAHPFQ-UHFFFAOYSA-N
mp   214-215 °C (lit.)
Featured Industry   Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to BP 458
  traceable to PhEur P4100000
  traceable to USP 1587001

Description

General description

Pyridoxine hydrochloride is a water soluble vitamin, widely used for the prevention of peripheral neuropathy and central nervous system effects associated with therapy involving isoniazid. It is highly required for the formation of hemoglobin and is also mainly involved in carbohydrate, fat and amino acid metabolism.

Application

Pyridoxine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations using reversed-phase high-performance liquid chromatography and spectrophotometric techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB3720 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles

Articles

HPLC Analysis of B-Vitamins in Vitamin Water using Ascentis® Express RP-Amide and UV Detection

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of B-Vitamins in Vitamin Water using Ascentis® Express RP-Amide and UV Detection
Keywords: Anticonvulsants, Chromatography, Pharmaceutical, Vitamins

HPLC Analysis of B-vitamins on Ascentis® Express RP-Amide using UV detection

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of B-vitamins on Ascentis® Express RP-Amide using UV detection
Keywords: Anticonvulsants, Chromatography, Pharmaceutical, Vitamins

HPLC Analysis of Water Soluble B Vitamins on Ascentis® Express RP-Amide

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Water Soluble B Vitamins on Ascentis® Express RP-Amide
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical, Vitamins

HPLC Analysis of Water-Soluble B-Vitamins on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Water-Soluble B-Vitamins on Ascentis® Express C18
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical, Vitamins

HPLC Analysis of Water-Soluble B-Vitamins on Ascentis® Express F5

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Water-Soluble B-Vitamins on Ascentis® Express F5
Keywords: Anticonvulsants, Chromatography, High performance liquid chromatography, Pharmaceutical, Vitamins

LC/MS/MS Analysis of Vitamins B1 and B6 on Ascentis® Express OH5

From our library of Articles, Sigma-Aldrich presents LC/MS/MS Analysis of Vitamins B1 and B6 on Ascentis® Express OH5
Keywords: Chromatography, High performance liquid chromatography, Mass spectrometry, Solvents, Vitamins

UHPLC Analysis of B Vitamins in Vitamin Water on Titan™ C18 using UV Detection

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of B Vitamins in Vitamin Water on Titan™ C18 using UV Detection
Keywords: Anticonvulsants, Chromatography, Pharmaceutical, Vitamins

UHPLC Analysis of B-vitamins on Titan™ C18 using UV detection

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of B-vitamins on Titan™ C18 using UV detection
Keywords: Anticonvulsants, Chromatography, Pharmaceutical, Vitamins

Peer-Reviewed Papers
15

References

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