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PHR1047 Supelco

Phenol

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: Hydroxybenzene

  • CAS Number 108-95-2

  • Linear Formula C6H5OH

  • Molecular Weight 94.11

  •  Beilstein/REAXYS Number 969616

  •  EC Number 203-632-7

  •  MDL number MFCD00002143

  •  PubChem Substance ID 329823077

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, Extractables and Leachables, Food & Beverage Standards, Food and Cosmetic Component Standards,
Quality Level   300
grade   certified reference material
  pharmaceutical secondary standard
vapor density   3.24 (vs air)
vapor pressure   0.09 psi ( 55 °C)
  0.36 mmHg ( 20 °C)
InChI Key   ISWSIDIOOBJBQZ-UHFFFAOYSA-N
autoignition temp.   1319 °F
expl. lim.   8.6 %
bp   182 °C (lit.)
mp   40-42 °C (lit.)
density   1.071 g/mL at 25 °C (lit.)
Featured Industry   Cleaning Products
Cosmetics
Food and Beverages
Personal Care
Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to USP 1524806

Description

General description

Phenol is a derivative of benzene and is majorly used in the manufacture of bisphenol A, phenolic resins and caprolactam. Its other applications include the manufacture of variety of compounds in pharma industry, dyes, explosives, rubber and agriculture.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Phenol may be used as a standard in determining the concentration of phenol present in samples of water using gas chromatography coupled with electron capture detector (GC-ECD).

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC1665 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

Signal word 
Danger
RIDADR 
UN 1671 6.1 / PGII
WGK Germany 
2
Flash Point(F) 
174.2 °F
Flash Point(C) 
79 °C
Protocols & Articles

Articles

GC Analysis of Phenols in Water on a 5% Phenyl Column after SPE using Supelclean™ ENVI-Chrom P

From our library of Articles, Sigma-Aldrich presents GC Analysis of Phenols in Water on a 5% Phenyl Column after SPE using Supelclean™ ENVI-Chrom P
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification, Sample preparations, Size-exclusion chromatography, Solid phase extractions

GC Analysis of Phenols in Water on a 5% Phenyl Column after SPME using 85 μm Polyacrylate Fiber

From our library of Articles, Sigma-Aldrich presents GC Analysis of Phenols in Water on a 5% Phenyl Column after SPME using 85 μm Polyacrylate Fiber
Keywords: Chromatography, Gas chromatography, Mass spectrometry, Purification, Size-exclusion chromatography, Solid phase microextractions

GC Analysis of Phenols on SLB®-5ms after SPME using 60 μm Carbowax® Fiber

From our library of Articles, Sigma-Aldrich presents GC Analysis of Phenols on SLB®-5ms after SPME using 60 μm Carbowax® Fiber
Keywords: Chromatography, Gas chromatography, Purification, Size-exclusion chromatography, Solid phase microextractions

HPLC Analysis of Cresols and Phenol on Astec® CYCLOBOND® I 2000

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Cresols and Phenol on Astec® CYCLOBOND® I 2000
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of Phenolic Compounds on Ascentis® Express 2.7 μm RP-Amide

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Phenolic Compounds on Ascentis® Express 2.7 μm RP-Amide
Keywords: Chromatography, High performance liquid chromatography, Vitamins

HPLC Analysis of Phenols on SUPELCOSIL™ LC-8

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Phenols on SUPELCOSIL™ LC-8
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of Polar and Non-Polar Analytes on Ascentis® Express C18, Column Test Mixture

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Polar and Non-Polar Analytes on Ascentis® Express C18, Column Test Mixture
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

US EPA Method 8041: GC Analysis of Phenols on Equity®-5

From our library of Articles, Sigma-Aldrich presents US EPA Method 8041: GC Analysis of Phenols on Equity®-5
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification, Size-exclusion chromatography

US EPA Method 8270: GC Analysis of Semivolatiles on Equity®-5

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on Equity®-5
Keywords: Chromatography, Gas chromatography, Mass selective detector, Purification

US EPA Method 8270: GC Analysis of Semivolatiles on SLB-5ms (20 m x 0.18 mm I.D., 0.36 μm), Fast GC Analysis

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on SLB-5ms (20 m x 0.18 mm I.D., 0.36 μm), Fast GC Analysis
Keywords: Chromatography, Gas chromatography, Purification

US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms (20 m x 0.18 mm I.D., 0.18 μm), Fast GC Analysis

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms (20 m x 0.18 mm I.D., 0.18 μm), Fast GC Analysis
Keywords: Chromatography, Gas chromatography, Purification, Size-exclusion chromatography

US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms (20 m x 0.18 mm I.D., 0.36 μm), 28 °C/min Oven Ramp, Fast GC Analysis

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms (20 m x 0.18 mm I.D., 0.36 μm), 28 °C/min Oven Ramp, Fast GC Analysis
Keywords: Chromatography, Gas chromatography, Purification

US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms (30 m x 0.25 mm I.D., 0.50 μm)

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms (30 m x 0.25 mm I.D., 0.50 μm)
Keywords: Chromatography, Gas chromatography, Purification

US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms, 350 °C Final Oven Temp.

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms, 350 °C Final Oven Temp.
Keywords: Chromatography, Gas chromatography

US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms
Keywords: Chromatography, Gas chromatography, Purification

US EPA Method OLM04.2 SVOA: GC Analysis of Semivolatiles on SLB®-5ms

From our library of Articles, Sigma-Aldrich presents US EPA Method OLM04.2 SVOA: GC Analysis of Semivolatiles on SLB®-5ms
Keywords: Chromatography, Gas chromatography, Purification

Peer-Reviewed Papers
15

References

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