EMAIL THIS PAGE TO A FRIEND
PHR1051 Supelco

Propylene glycol

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: 1,2-Propanediol, Propylene glycol

  • CAS Number 57-55-6

  • Linear Formula CH3CH(OH)CH2OH

  • Molecular Weight 76.09

  •  Beilstein/REAXYS Number 1340498

  •  EC Number 200-338-0

  •  MDL number MFCD00064272

  •  PubChem Substance ID 329823081

  •  E Number E1520

  •  NACRES NA.24

Purchase

Properties

Related Categories Additional Standards, Alcohol, All Alphabetically Sorted, Analytical Standards, Analytical/Chromatography,
grade   certified reference material
  pharmaceutical secondary standard
vapor density   2.62 (vs air)
vapor pressure   0.08 mmHg ( 20 °C)
InChI Key   DNIAPMSPPWPWGF-UHFFFAOYSA-N
form   neat
autoignition temp.   779 °F
expl. lim.   12.5 %
refractive index   n20/D 1.432 (lit.)
bp   187 °C (lit.)
mp   −60 °C (lit.)
density   1.036 g/mL at 25 °C (lit.)
Featured Industry   Cleaning Products
Cosmetics
Food and Beverages
Personal Care
Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to USP 1576708

Description

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Propylene glycol is commonly utilized as a penetration enhancer in topical dermatological formulations, either alone or in combined form with other penetration enhancing agents, like fatty acids.

Application

Propylene glycol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB9658 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
TY2000000
Flash Point(F) 
217.4 °F
Flash Point(C) 
103 °C
Protocols & Articles

Articles

GC Analysis of Alkyldiol Enantiomers on Astec® CHIRALDEX® G-TA

From our library of Articles, Sigma-Aldrich presents GC Analysis of Alkyldiol Enantiomers on Astec® CHIRALDEX® G-TA
Keywords: Chromatography, Gas chromatography, Purification

GC Analysis of Glycols in Water on SPB®-1000 after SPE using ENVI-Carb™ Plus

From our library of Articles, Sigma-Aldrich presents GC Analysis of Glycols in Water on SPB®-1000 after SPE using ENVI-Carb™ Plus
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification, Sample preparations, Solid phase extractions

GC Analysis of Glycols on Nukol™

From our library of Articles, Sigma-Aldrich presents GC Analysis of Glycols on Nukol™
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification

Related Content

Flavor and Fragrance Analysis

We offer quality product solutions in all three stages of analysis to help achieve fast, accurate results. Below, you can learn more about our workflow solutions for sample preparation, separation, d...
Keywords: Calorimetry, Chromatography, Environmental, Gas chromatography, Mass spectrometry, Pesticides, Sample preparations, Separation

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?