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PHR1086 Supelco

Acetanilide melting point standard

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: N-Phenylacetamide, Acetanilide

  • CAS Number 103-84-4

  • Linear Formula CH3CONHC6H5

  • Molecular Weight 135.16

  •  Beilstein/REAXYS Number 606468

  •  EC Number 203-150-7

  •  MDL number MFCD00008674

  •  eCl@ss 39031308

  •  PubChem Substance ID 329823108

  •  NACRES NA.24

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Properties

Related Categories A-B, Analytical Standards, Analytical/Chromatography, Pharmaceutical Secondary Standards, Pharmacopeia & Metrological Institutes Standards More...
Quality Level   300
grade   certified reference material
  pharmaceutical secondary standard
vapor density   4.65 (vs air)
vapor pressure   1 mmHg ( 114 °C)
form   neat
autoignition temp.   1004 °F
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
bp   304 °C (lit.)
mp   ~Approximately 115 °C
  113-115 °C (lit.)
Featured Industry   Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to USP 1004001
SMILES string   CC(=O)Nc1ccccc1
InChI   1S/C8H9NO/c1-7(10)9-8-5-3-2-4-6-8/h2-6H,1H3,(H,9,10)
InChI key   FZERHIULMFGESH-UHFFFAOYSA-N

Description

General description

Acetanilide belongs to a class of compounds which are the active components of drugs exhibiting analgesic and antipyretic properties.

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Acetanilide has been used as a calibration standard for the development of a test for the evaluation of acetanilide by thermal analyses methods.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA7127 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
RTECS 
AD7350000
Flash Point(F) 
321.8 °F - closed cup
Flash Point(C) 
161 °C - closed cup
Protocols & Articles

Articles

HPLC Analysis of Analgesics on Discovery® HS F5

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Analgesics on Discovery® HS F5
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

Peer-Reviewed Papers
15

References

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