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PHR1097 Supelco

L-Tyrosine

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: (S)-2-Amino-3-(4-hydroxyphenyl)propionic acid, 3-(4-Hydroxyphenyl)-L-alanine

  • CAS Number 60-18-4

  • Linear Formula 4-(HO)C6H4CH2CH(NH2)CO2H

  • Molecular Weight 181.19

  •  Beilstein/REAXYS Number 392441

  •  EC Number 200-460-4

  •  MDL number MFCD00002606

  •  PubChem Substance ID 329823119

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, N-Acetyl-L-Tyrosine Impurities, Pharmaceutical Impurities, Pharmaceutical Secondary Standards,
Quality Level   300
grade   certified reference material
  pharmaceutical secondary standard
mp   >300 °C (dec.) (lit.)
Featured Industry   Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to PhEur T2900000
  traceable to USP 1705006
SMILES string   N[C@@H](Cc1ccc(O)cc1)C(O)=O
InChI   1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1
InChI key   OUYCCCASQSFEME-QMMMGPOBSA-N

Description

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

L-Tyrosine may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by a liquid chromatography technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Other Notes

Amino acid precursor of dopamine and other catecholamines

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA7163 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

GC Analysis of Amino Acids (as TBDMS Derivatives) on SLB®-5ms (20 m x 0.18 mm I.D., 0.18 μm), Fast GC Analysis

From our library of Articles, Sigma-Aldrich presents GC Analysis of Amino Acids (as TBDMS Derivatives) on SLB®-5ms (20 m x 0.18 mm I.D., 0.18 μm), Fast GC Analysis
Keywords: Chromatography, Gas chromatography, Purification

HPLC Analysis of Tyrosine Enantiomers on Astec® CHIROBIOTIC® T

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Tyrosine Enantiomers on Astec® CHIROBIOTIC® T
Keywords: Chromatography, High performance liquid chromatography

Peer-Reviewed Papers
15

References

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