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PHR1103 Supelco

L-Serine

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: (S)-2-Amino-3-hydroxypropionic acid

  • CAS Number 56-45-1

  • Linear Formula HOCH2CH(NH2)CO2H

  • Molecular Weight 105.09

  •  Beilstein/REAXYS Number 1721404

  •  EC Number 200-274-3

  •  MDL number MFCD00064224

  •  eCl@ss 32160406

  •  PubChem Substance ID 329823125

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, P-S, Pharmaceutical Secondary Standards, Pharmacopeia & Metrological Institutes Standards More...
Quality Level   300
grade   certified reference material
  pharmaceutical secondary standard
InChI Key   MTCFGRXMJLQNBG-REOHCLBHSA-N
form   neat
mp   222 °C (dec.) (lit.)
Featured Industry   Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to PhEur S0450000
  traceable to USP 1612506

Description

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

L-Serine may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by ion chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Precursor of glycine by serine hydroxymethyltransferase.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA7166 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
VT8100000

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles

Articles

GC Analysis of Amino Acids (as TBDMS Derivatives) on SLB®-5ms (20 m x 0.18 mm I.D., 0.18 μm), Fast GC Analysis

From our library of Articles, Sigma-Aldrich presents GC Analysis of Amino Acids (as TBDMS Derivatives) on SLB®-5ms (20 m x 0.18 mm I.D., 0.18 μm), Fast GC Analysis
Keywords: Chromatography, Gas chromatography, Purification

HPLC Analysis of Amino Acids on Ascentis® Si (Silica), HILIC Mode

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Amino Acids on Ascentis® Si (Silica), HILIC Mode
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of Polar Neutral and Acidic Amino Acids on Ascentis® Si (Silica)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Polar Neutral and Acidic Amino Acids on Ascentis® Si (Silica)
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of Serine Enantiomers on Astec® CHIROBIOTIC® T (Formic Acid Mobile Phase Additive)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Serine Enantiomers on Astec® CHIROBIOTIC® T (Formic Acid Mobile Phase Additive)
Keywords: Chromatography, High performance liquid chromatography

Peer-Reviewed Papers
15

References

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