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PHR1128 Supelco

Bupivacaine hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: 1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide, Bupivacaine hydrochloride monohydrate

  • CAS Number 73360-54-0

  • Empirical Formula (Hill Notation) C18H28N2O · HCl · H2O

  • Molecular Weight 342.90

  •  MDL number MFCD00941462

  •  PubChem Substance ID 329823149

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Properties

Related Categories A-C, A-H, Additional Standards, Analytical Standards, Analytical/Chromatography,
grade   certified reference material
  pharmaceutical secondary standard
InChI Key   HUCIWBPMHXGLFM-UHFFFAOYSA-N
form   neat
Featured Industry   Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to BP 479
  traceable to PhEur B1160000
  traceable to USP 1078507

Description

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Biochem/physiol Actions

Sodium channel blocker, local anesthetic.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA6762 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGII
WGK Germany 
3

Documents

Certificate of Analysis

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Protocols & Articles

Articles

GC Analysis of Bupivacaine Enantiomers on Astec® CHIRALDEX® B-PH

From our library of Articles, Sigma-Aldrich presents GC Analysis of Bupivacaine Enantiomers on Astec® CHIRALDEX® B-PH
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Pharmaceutical, Purification

HPLC Analysis of Bupivacaine Enantiomers on Astec® CHIROBIOTIC® V2, Acetate Mobile Phase

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Bupivacaine Enantiomers on Astec® CHIROBIOTIC® V2, Acetate Mobile Phase
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Bupivacaine Enantiomers on Astec® CHIROBIOTIC® V2, Formate Mobile Phase

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Bupivacaine Enantiomers on Astec® CHIROBIOTIC® V2, Formate Mobile Phase
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Bupivacaine Enantiomers on Astec® CHIROBIOTIC® V

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Bupivacaine Enantiomers on Astec® CHIROBIOTIC® V
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

Thin Layer Chromatography Identification Test for Bupivacaine following European Pharmacopeia Monograph on Silica Gel G F 254 Plates

Bupivacaine, often marketed under the brand name Marcaine, is used for local infiltration, peripheral nerve block, sympathetic nerve block, and epidural and caudal blocks. It is on the World Health O...
Keywords: Thin layer chromatography

Peer-Reviewed Papers
15

References

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