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PHR1150 Supelco

Acetaminophen Related Compound F

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: 4-Nitrophenol, p-Nitrophenol, Paracetamol Impurity F

  • CAS Number 100-02-7

  • Linear Formula O2NC6H4OH

  • Molecular Weight 139.11

  •  Beilstein/REAXYS Number 1281877

  •  EC Number 202-811-7

  •  MDL number MFCD00007331

  •  PubChem Substance ID 329823168

  •  NACRES NA.24

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Properties

Related Categories A-B, Acetaminophen Impurities, Analytical Standards, Analytical/Chromatography, Paracetamol (Acetaminophen) Impurities,
grade   certified reference material
  pharmaceutical secondary standard
vapor pressure   0.6 mmHg ( 120 °C)
InChI Key   BTJIUGUIPKRLHP-UHFFFAOYSA-N
form   neat
autoignition temp.   541 °F
bp   279 °C (lit.)
mp   110-115 °C (lit.)
Featured Industry   Pharmaceutical (small molecule)
format   neat

Description

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Values of analytes vary lot to lot.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA8987 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 1663 6.1 / PGIII
WGK Germany 
2
Flash Point(F) 
336.2 °F
Flash Point(C) 
169 °C
Protocols & Articles

Articles

GC Analysis of Phenols in Water on a 5% Phenyl Column after SPE using Supelclean™ ENVI-Chrom P

From our library of Articles, Sigma-Aldrich presents GC Analysis of Phenols in Water on a 5% Phenyl Column after SPE using Supelclean™ ENVI-Chrom P
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification, Sample preparations, Size-exclusion chromatography, Solid phase extractions

GC Analysis of Phenols in Water on a 5% Phenyl Column after SPME using 85 μm Polyacrylate Fiber

From our library of Articles, Sigma-Aldrich presents GC Analysis of Phenols in Water on a 5% Phenyl Column after SPME using 85 μm Polyacrylate Fiber
Keywords: Chromatography, Gas chromatography, Mass spectrometry, Purification, Size-exclusion chromatography, Solid phase microextractions

GC Analysis of Phenols on SLB®-5ms after SPME using 60 μm Carbowax® Fiber

From our library of Articles, Sigma-Aldrich presents GC Analysis of Phenols on SLB®-5ms after SPME using 60 μm Carbowax® Fiber
Keywords: Chromatography, Gas chromatography, Purification, Size-exclusion chromatography, Solid phase microextractions

HPLC Analysis of Phenols on SUPELCOSIL™ LC-8

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Phenols on SUPELCOSIL™ LC-8
Keywords: Chromatography, High performance liquid chromatography

US EPA Method 625: GC Analysis of Semivolatiles on SLB®-5ms

From our library of Articles, Sigma-Aldrich presents US EPA Method 625: GC Analysis of Semivolatiles on SLB®-5ms
Keywords: Chromatography, Gas chromatography, Purification

US EPA Method 8041: GC Analysis of Phenols on Equity®-5

From our library of Articles, Sigma-Aldrich presents US EPA Method 8041: GC Analysis of Phenols on Equity®-5
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification, Size-exclusion chromatography

US EPA Method 8270: GC Analysis of Semivolatiles on Equity®-5

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on Equity®-5
Keywords: Chromatography, Gas chromatography, Mass selective detector, Purification

US EPA Method 8270: GC Analysis of Semivolatiles on SLB-5ms (20 m x 0.18 mm I.D., 0.36 μm), Fast GC Analysis

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on SLB-5ms (20 m x 0.18 mm I.D., 0.36 μm), Fast GC Analysis
Keywords: Chromatography, Gas chromatography, Purification

US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms (20 m x 0.18 mm I.D., 0.18 μm), Fast GC Analysis

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms (20 m x 0.18 mm I.D., 0.18 μm), Fast GC Analysis
Keywords: Chromatography, Gas chromatography, Purification, Size-exclusion chromatography

US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms (20 m x 0.18 mm I.D., 0.36 μm), 28 °C/min Oven Ramp, Fast GC Analysis

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms (20 m x 0.18 mm I.D., 0.36 μm), 28 °C/min Oven Ramp, Fast GC Analysis
Keywords: Chromatography, Gas chromatography, Purification

US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms (30 m x 0.25 mm I.D., 0.50 μm)

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms (30 m x 0.25 mm I.D., 0.50 μm)
Keywords: Chromatography, Gas chromatography, Purification

US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms
Keywords: Chromatography, Gas chromatography, Purification

US EPA Method OLM04.2 SVOA: GC Analysis of Semivolatiles on SLB®-5ms

From our library of Articles, Sigma-Aldrich presents US EPA Method OLM04.2 SVOA: GC Analysis of Semivolatiles on SLB®-5ms
Keywords: Chromatography, Gas chromatography, Purification

Peer-Reviewed Papers
15

References

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PHR1005 Acetaminophen, Pharmaceutical Secondary Standard; Certified Reference Material

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