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PHR1158 Supelco

Benzocaine

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: 4-Aminobenzoic acid ethyl ester, Ethyl 4-aminobenzoate

  • CAS Number 94-09-7

  • Empirical Formula (Hill Notation) C9H11NO2

  • Molecular Weight 165.19

  •  Beilstein/REAXYS Number 638434

  •  EC Number 202-303-5

  •  MDL number MFCD00007892

  •  PubChem Substance ID 329823176

  •  NACRES NA.24

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Properties

Related Categories A-B, Analytical Standards, Analytical/Chromatography, Pharmaceutical Secondary Standards, Pharmacopeia & Metrological Institutes Standards More...
Quality Level   300
grade   certified reference material
  pharmaceutical secondary standard
form   neat
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
Featured Industry   Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to USP 1054000
SMILES string   CCOC(=O)c1ccc(N)cc1
InChI   1S/C9H11NO2/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6H,2,10H2,1H3
InChI key   BLFLLBZGZJTVJG-UHFFFAOYSA-N

Description

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Benzocaine is an ester-type local anesthetic, able to induce pain relief. It is used extensively in topical, mucosal and dermal formulations.

Application

Benzocaine may be used as a pharmaceutical reference standard for the determination of the analyte in bioadhesive gel, pharmaceutical formulations and channel catfish tissues by various chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Values of analytes vary lot to lot.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA6506 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
233.6 °F
Flash Point(C) 
112 °C

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles

Articles

HPLC Analysis of Anesthetics, Local on Ascentis® Phenyl

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Anesthetics, Local on Ascentis® Phenyl
Keywords: Chromatography, Clinical, High performance liquid chromatography, Pharmaceutical

Peer-Reviewed Papers
15

References

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