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PHR1200 Supelco

p-Chloroaniline

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: 4-Chloroaniline

  • CAS Number 106-47-8

  • Linear Formula ClC6H4NH2

  • Molecular Weight 127.57

  •  Beilstein/REAXYS Number 471359

  •  EC Number 203-401-0

  •  MDL number MFCD00007835

  •  PubChem Substance ID 329823207

  •  NACRES NA.24

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Properties

Related Categories Additional Standards, Analytical Standards, Analytical/Chromatography, C-D, Chlorhexidine Metabolite,
Quality Level   300
grade   certified reference material
  pharmaceutical secondary standard
vapor density   4.4 (vs air)
vapor pressure   0.15 mmHg ( 25 °C)
form   neat
bp   232 °C (lit.)
mp   67-70 °C (lit.)
Featured Industry   Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to USP 1111908
SMILES string   Nc1ccc(Cl)cc1
InChI   1S/C6H6ClN/c7-5-1-3-6(8)4-2-5/h1-4H,8H2
InChI key   QSNSCYSYFYORTR-UHFFFAOYSA-N

Description

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

p-Chloroaniline may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC3328 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
RIDADR 
UN 2018 6.1 / PGII
WGK Germany 
WGK 3
RTECS 
BX0700000
Flash Point(F) 
248.0 °F - closed cup
Flash Point(C) 
120.0 °C - closed cup

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles

Articles

GC Analysis of Semivolatiles on SLB®-5ms after SPME using 60 μm Carbowax® Fiber

From our library of Articles, Sigma-Aldrich presents GC Analysis of Semivolatiles on SLB®-5ms after SPME using 60 μm Carbowax® Fiber
Keywords: Chromatography, Gas chromatography, Purification, Solid phase microextractions

GC Analysis of a 32-Component Anilines Mix on SLB®-IL59

From our library of Articles, Sigma-Aldrich presents GC Analysis of a 32-Component Anilines Mix on SLB®-IL59
Keywords: Chromatography, Gas chromatography, Mass selective detector

US EPA Method 8270: GC Analysis of Semivolatiles on Equity®-5

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on Equity®-5
Keywords: Chromatography, Gas chromatography, Mass selective detector, Purification

US EPA Method 8270: GC Analysis of Semivolatiles on SLB-5ms (20 m x 0.18 mm I.D., 0.36 μm), Fast GC Analysis

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on SLB-5ms (20 m x 0.18 mm I.D., 0.36 μm), Fast GC Analysis
Keywords: Chromatography, Gas chromatography, Purification

US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms (20 m x 0.18 mm I.D., 0.18 μm), Fast GC Analysis

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms (20 m x 0.18 mm I.D., 0.18 μm), Fast GC Analysis
Keywords: Chromatography, Gas chromatography, Purification, Size-exclusion chromatography

US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms (20 m x 0.18 mm I.D., 0.36 μm), 28 °C/min Oven Ramp, Fast GC Analysis

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms (20 m x 0.18 mm I.D., 0.36 μm), 28 °C/min Oven Ramp, Fast GC Analysis
Keywords: Chromatography, Gas chromatography, Purification

US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms (30 m x 0.25 mm I.D., 0.50 μm)

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms (30 m x 0.25 mm I.D., 0.50 μm)
Keywords: Chromatography, Gas chromatography, Purification

US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms, 350 °C Final Oven Temp.

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms, 350 °C Final Oven Temp.
Keywords: Chromatography, Gas chromatography

US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms
Keywords: Chromatography, Gas chromatography, Purification

Peer-Reviewed Papers
15

References

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