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PHR1209 Supelco

1-Butanol

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: n-Butanol, Butyl alcohol

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Properties

Related Categories A-B, Analytical Standards, Analytical/Chromatography, Chinese Food Contact Materials Regulation GB 9685 2016, Food & Beverage Standards,
Quality Level   300
grade   certified reference material
  pharmaceutical secondary standard
vapor density   2.55 (vs air)
form   neat
autoignition temp.   649 °F
expl. lim.   11.2 %
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
refractive index   n20/D 1.399 (lit.)
bp   116-118 °C (lit.)
mp   −90 °C (lit.)
density   0.81 g/mL at 25 °C (lit.)
Featured Industry   Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to USP 1081807
SMILES string   CCCCO
InChI   1S/C4H10O/c1-2-3-4-5/h5H,2-4H2,1H3
InChI key   LRHPLDYGYMQRHN-UHFFFAOYSA-N

Description

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. 1-Butanol is a potential fuel substitute to gasoline. It is also a feedstock used to produce chemicals. It is produced via two pathways, the synthetic 2-ketoacid pathway and CoA-dependent pathway. It can also be produced by fermentation of biomass-derived carbohydrates.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA9022 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
RIDADR 
UN1120 - class 3 - PG 3 - Butanols
WGK Germany 
WGK 1
RTECS 
EO1400000
Flash Point(F) 
95.0 °F - Pensky-Martens closed cup
Flash Point(C) 
35 °C - Pensky-Martens closed cup
Protocols & Articles

Articles

GC Analysis of Alcoholic Spirit on Equity®-1 °Coupled to SUPELCOWAX 10 (Column Set 2)

From our library of Articles, Sigma-Aldrich presents GC Analysis of Alcoholic Spirit on Equity®-1 °Coupled to SUPELCOWAX 10 (Column Set 2)
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification, Size-exclusion chromatography

GC Analysis of Alcohols on PAG

From our library of Articles, Sigma-Aldrich presents GC Analysis of Alcohols on PAG
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification

GC Analysis of Class 3 Residual Solvents on OVI-G43

From our library of Articles, Sigma-Aldrich presents GC Analysis of Class 3 Residual Solvents on OVI-G43
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Pharmaceutical, Size-exclusion chromatography

GC Analysis of Class 3 Residual Solvents on SUPELCOWAX® 10

From our library of Articles, Sigma-Aldrich presents GC Analysis of Class 3 Residual Solvents on SUPELCOWAX® 10
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Pharmaceutical, Size-exclusion chromatography

GC Analysis of Class 3 Residual Solvents on VOCOL® after SPME using 100 μm PDMS Fiber

From our library of Articles, Sigma-Aldrich presents GC Analysis of Class 3 Residual Solvents on VOCOL® after SPME using 100 μm PDMS Fiber
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Pharmaceutical, Size-exclusion chromatography, Solid phase microextractions

GC Analysis of Industrial Solvents on Equity®-1701

From our library of Articles, Sigma-Aldrich presents GC Analysis of Industrial Solvents on Equity®-1701
Keywords: Chromatography, Flame ionization detector, Gas chromatography

GC Analysis of Industrial Solvents on Equity®-1

From our library of Articles, Sigma-Aldrich presents GC Analysis of Industrial Solvents on Equity®-1
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification, Size-exclusion chromatography

GC Analysis of Industrial Solvents on SUPELCOWAX 10

From our library of Articles, Sigma-Aldrich presents GC Analysis of Industrial Solvents on SUPELCOWAX 10
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification

GC Analysis of a 56-Component Industrial Solvents Mix on SLB®-IL60, Comparison to a Polyethylene Glycol (PEG) Column

From our library of Articles, Sigma-Aldrich presents GC Analysis of a 56-Component Industrial Solvents Mix on SLB®-IL60, Comparison to a Polyethylene Glycol (PEG) Column
Keywords: Chromatography, Flame ionization detector, Gas chromatography

GC Analysis of an Indoor Air Standard on Equity®-1

From our library of Articles, Sigma-Aldrich presents GC Analysis of an Indoor Air Standard on Equity®-1
Keywords: Air Monitoring, Chromatography, Gas chromatography, Purification, Size-exclusion chromatography

Peer-Reviewed Papers
15

References

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