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PHR1223 Supelco

2-Methylpyrazine

Pharmaceutical Secondary Standard; Certified Reference Material

  • CAS Number 109-08-0

  • Empirical Formula (Hill Notation) C5H6N2

  • Molecular Weight 94.11

  •  Beilstein/REAXYS Number 105778

  •  EC Number 203-645-8

  •  MDL number MFCD00006142

  •  PubChem Substance ID 329823229

  •  NACRES NA.24

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Properties

Related Categories Alcoholic & Nonalcoholic Beverages, All Alphabetically Sorted, Almond, Analytical Standards, Analytical/Chromatography,
Quality Level   300
grade   certified reference material
  pharmaceutical secondary standard
form   neat
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
refractive index   n20/D 1.504 (lit.)
bp   135 °C/761 mmHg (lit.)
mp   −29 °C (lit.)
density   1.03 g/mL at 25 °C (lit.)
Featured Industry   Cleaning Products
Cosmetics
Flavors and Fragrances
Food and Beverages
Personal Care
Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to PhEur Y0001376
SMILES string   Cc1cnccn1
InChI   1S/C5H6N2/c1-5-4-6-2-3-7-5/h2-4H,1H3
InChI key   CAWHJQAVHZEVTJ-UHFFFAOYSA-N

Description

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. 2-Methylpyrazine is one of the major flavor volatiles reported in rice cakes, roasted peanuts and soybean products.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA9035 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
UN 1993C 3 / PGIII
WGK Germany 
WGK 3
RTECS 
UQ3675000
Flash Point(F) 
122.0 °F - closed cup
Flash Point(C) 
50 °C - closed cup

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

GC Analysis of Pyrazines in Peanut Butter on SUPELCOWAX® 10 after SPME using 50/30 μm DVB/Carboxen/PDMS Fiber

From our library of Articles, Sigma-Aldrich presents GC Analysis of Pyrazines in Peanut Butter on SUPELCOWAX® 10 after SPME using 50/30 μm DVB/Carboxen/PDMS Fiber
Keywords: Chromatography, Gas chromatography, Mass spectrometry, Purification, Separation, Size-exclusion chromatography, Solid phase microextractions

GC Analysis of Volatiles in Roasted Coffee Beans on Omegawax® after SPME using a 50/30 μm DVB/Carboxen/PDMS Fiber

From our library of Articles, Sigma-Aldrich presents GC Analysis of Volatiles in Roasted Coffee Beans on Omegawax® after SPME using a 50/30 μm DVB/Carboxen/PDMS Fiber
Keywords: Chromatography, Gas chromatography, Mass spectrometry, Purification, Size-exclusion chromatography, Solid phase microextractions

Related Content

Flavor and Fragrance Analysis

We offer quality product solutions in all three stages of analysis to help achieve fast, accurate results. Below, you can learn more about our workflow solutions for sample preparation, separation, d...
Keywords: Calorimetry, Chromatography, Environmental, Gas chromatography, Mass spectrometry, Pesticides, Sample preparations, Separation

Peer-Reviewed Papers
15

References

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