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PHR1266 Supelco

Acesulfame K

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: 6-Methyl-1,2,3-oxathiazin-4(3H)-one 2,2-dioxide potassium salt

  • CAS Number 55589-62-3

  • Empirical Formula (Hill Notation) C4H4KNO4S

  • Molecular Weight 201.24

  •  Beilstein/REAXYS Number 3637857

  •  EC Number 259-715-3

  •  MDL number MFCD00043833

  •  PubChem Substance ID 329823262

  •  E Number E950

  •  NACRES NA.24

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Properties

Related Categories A-B, Analytical Standards, Analytical/Chromatography, E numbers (Food Additives), E900–E999 (miscellaneous),
Quality Level   300
grade   certified reference material
  pharmaceutical secondary standard
form   neat
Featured Industry   Cleaning Products
Cosmetics
Food and Beverages
Personal Care
Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to PhEur A0070000
  traceable to USP 1002505
SMILES string   [K+].CC1=CC(=O)[N-]S(=O)(=O)O1
InChI   1S/C4H5NO4S.K/c1-3-2-4(6)5-10(7,8)9-3;/h2H,1H3,(H,5,6);/q;+1/p-1
InChI key   WBZFUFAFFUEMEI-UHFFFAOYSA-M

Description

General description

Acesulfame K is a synthetically prepared sulfonyl amide sweetener, widely used with sugar alcohols in food and beverage industry.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Acesulfame K may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using capillary zone electrophoresis and ion chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC1663 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
RP4489165

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles
Peer-Reviewed Papers
15

References

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