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PHR1439 Supelco

Beta-Cyclodextrin

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: β-Cyclodextrin, Caraway, Cycloheptaamylose, Cyclomaltoheptaose, Schardinger β-Dextrin

  • CAS Number 7585-39-9

  • Empirical Formula (Hill Notation) C42H70O35

  • Molecular Weight 1134.98

  •  Beilstein/REAXYS Number 78623

  •  EC Number 231-493-2

  •  MDL number MFCD00078139

  •  PubChem Substance ID 329822602

  •  NACRES NA.24

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Properties

Related Categories A-B, A-F, All Alphabetically Sorted, Analytical Standards, Analytical/Chromatography,
grade   certified reference material
  pharmaceutical secondary standard
InChI Key   WHGYBXFWUBPSRW-FOUAGVGXSA-N
optical activity   [α]20/D +162±3°, c = 1.5% in H2O
mp   290-300 °C (dec.) (lit.)
Featured Industry   Cleaning Products
Cosmetics
Food and Beverages
Personal Care
Pharmaceutical (small molecule)
analyte suitability   oligosaccharides
format   neat
pharmacopeia traceability   traceable to USP 1154569

Description

General description

Beta-Cyclodextrin is the most abundant and cheap cyclic oligosaccharide that forms inclusion complexes with several drug molecules. Its main application is in tablet and capsule formulations.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Beta-Cyclodextrin may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA2747 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Setting the Standard for Solid Formulation
Protocols & Articles

Articles

HPLC Analysis of Oligosaccharides from Dark Corn Syrup on SUPELCOGEL™ Ag

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Oligosaccharides from Dark Corn Syrup on SUPELCOGEL™ Ag
Keywords: Chromatography, High performance liquid chromatography

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Peer-Reviewed Papers
15

References

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