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PHR1446 Supelco

Ramipril

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: Tritace, [2S,3aS,6aS]-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid

  • CAS Number 87333-19-5

  • Empirical Formula (Hill Notation) C23H32N2O5

  • Molecular Weight 416.51

  •  MDL number MFCD00865775

  •  PubChem Substance ID 329822606

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, P-S, Pharmaceutical Secondary Standards, Pharmacopeia & Metrological Institutes Standards More...
grade   certified reference material
  pharmaceutical secondary standard
InChI Key   HDACQVRGBOVJII-JBDAPHQKSA-N
packaging   pkg of 1 g
Featured Industry   Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to BP 751
  traceable to PhEur R0145000
  traceable to USP 1598303

Description

General description

Ramipril is an angiotensin-converting-enzyme (ACE) inhibitor, which acts on the renin angiotensin aldosterone system. It is widely used in reducing hypertension by the suppression of the effects of angiotensin II at its receptor, thereby blocking the renin-angiotensin system.

Application

Ramipril may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using spectrophotometric technique and high-performance liquid chromatography technique.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Angiotensin converting enzyme (ACE) inhibitor.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC3757 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles
Peer-Reviewed Papers
15

References

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