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PHR1481 Supelco

Ethyl Acetate

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: EtOAc, Ethyl acetate

  • CAS Number 141-78-6

  • Linear Formula CH3COOC2H5

  • Molecular Weight 88.11

  •  Beilstein/REAXYS Number 506104

  •  EC Number 205-500-4

  •  MDL number MFCD00009171

  •  PubChem Substance ID 329823409

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, E-J, Extractables and Leachables, Food & Beverage Standards,
grade   certified reference material
  pharmaceutical secondary standard
vapor density   3 (20 °C, vs air)
vapor pressure   73 mmHg ( 20 °C)
InChI Key   XEKOWRVHYACXOJ-UHFFFAOYSA-N
autoignition temp.   801 °F
expl. lim.   2.2-11.5 %, 38 °F
packaging   ampule of 3x1.2 mL each
refractive index   n20/D 1.3720 (lit.)
bp   76.5-77.5 °C (lit.)
mp   −84 °C (lit.)
solubility   soluble
  water: soluble
density   0.902 g/mL at 25 °C (lit.)
Featured Industry   Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to USP 1265402

Description

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC0774 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Supplemental Hazard Statements 
Repeated exposure may cause skin dryness or cracking.
RIDADR 
UN1173 - class 3 - PG 2 - Ethyl acetate
WGK Germany 
1
Flash Point(F) 
26.6 °F
Flash Point(C) 
-3 °C
Protocols & Articles

Articles

GC Analysis of Alcoholic Spirit on Equity®-1 °Coupled to SUPELCOWAX 10 (Column Set 2)

From our library of Articles, Sigma-Aldrich presents GC Analysis of Alcoholic Spirit on Equity®-1 °Coupled to SUPELCOWAX 10 (Column Set 2)
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification, Size-exclusion chromatography

GC Analysis of Class 3 Residual Solvents on Equity®-1 after SPME using 100 μm PDMS Fiber

From our library of Articles, Sigma-Aldrich presents GC Analysis of Class 3 Residual Solvents on Equity®-1 after SPME using 100 μm PDMS Fiber
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Pharmaceutical, Size-exclusion chromatography, Solid phase microextractions

GC Analysis of Class 3 Residual Solvents on Equity®-5

From our library of Articles, Sigma-Aldrich presents GC Analysis of Class 3 Residual Solvents on Equity®-5
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Pharmaceutical, Size-exclusion chromatography

GC Analysis of Class 3 Residual Solvents on OVI-G43

From our library of Articles, Sigma-Aldrich presents GC Analysis of Class 3 Residual Solvents on OVI-G43
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Pharmaceutical, Size-exclusion chromatography

GC Analysis of Class 3 Residual Solvents on SUPELCOWAX® 10

From our library of Articles, Sigma-Aldrich presents GC Analysis of Class 3 Residual Solvents on SUPELCOWAX® 10
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Pharmaceutical, Size-exclusion chromatography

GC Analysis of Class 3 Residual Solvents on VOCOL® after SPME using 100 μm PDMS Fiber

From our library of Articles, Sigma-Aldrich presents GC Analysis of Class 3 Residual Solvents on VOCOL® after SPME using 100 μm PDMS Fiber
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Pharmaceutical, Size-exclusion chromatography, Solid phase microextractions

GC Analysis of Fermentation Compounds on a Packed Column (6.6% Carbowax® 20M on 80/120 °Carbopack™ B AW)

From our library of Articles, Sigma-Aldrich presents GC Analysis of Fermentation Compounds on a Packed Column (6.6% Carbowax® 20M on 80/120 °Carbopack™ B AW)
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification

GC Analysis of Industrial Solvents on Equity®-1701

From our library of Articles, Sigma-Aldrich presents GC Analysis of Industrial Solvents on Equity®-1701
Keywords: Chromatography, Flame ionization detector, Gas chromatography

GC Analysis of Industrial Solvents on Equity®-1

From our library of Articles, Sigma-Aldrich presents GC Analysis of Industrial Solvents on Equity®-1
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification, Size-exclusion chromatography

GC Analysis of Industrial Solvents on SUPELCOWAX 10

From our library of Articles, Sigma-Aldrich presents GC Analysis of Industrial Solvents on SUPELCOWAX 10
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification

GC Analysis of Residual Solvents on Equity®-5

From our library of Articles, Sigma-Aldrich presents GC Analysis of Residual Solvents on Equity®-5
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Pharmaceutical, Purification, Size-exclusion chromatography

GC Analysis of Scotch Whiskey on a Packed Column (5% Carbowax® 20M on 80/120 °Carbopack B)

From our library of Articles, Sigma-Aldrich presents GC Analysis of Scotch Whiskey on a Packed Column (5% Carbowax® 20M on 80/120 °Carbopack B)
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification

GC Analysis of Scotch Whiskey on a Packed Column (6.6% Carbowax® 20M on 80/120 °Carbopack B AW)

From our library of Articles, Sigma-Aldrich presents GC Analysis of Scotch Whiskey on a Packed Column (6.6% Carbowax® 20M on 80/120 °Carbopack B AW)
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification

GC Analysis of Solvents in Water on SPB®-1 SULFUR after SPME using 75 μm Carboxen/PDMS Fiber

From our library of Articles, Sigma-Aldrich presents GC Analysis of Solvents in Water on SPB®-1 SULFUR after SPME using 75 μm Carboxen/PDMS Fiber
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification, Solid phase microextractions, Solvents

GC Analysis of Solvents on a Packed Column (3% SP-1500 on Carbopack™ B)

From our library of Articles, Sigma-Aldrich presents GC Analysis of Solvents on a Packed Column (3% SP-1500 on Carbopack™ B)
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification

GC Analysis of Volatiles in Roasted Coffee Beans on Omegawax® after SPME using a 50/30 μm DVB/Carboxen/PDMS Fiber

From our library of Articles, Sigma-Aldrich presents GC Analysis of Volatiles in Roasted Coffee Beans on Omegawax® after SPME using a 50/30 μm DVB/Carboxen/PDMS Fiber
Keywords: Chromatography, Gas chromatography, Mass spectrometry, Purification, Size-exclusion chromatography, Solid phase microextractions

GC Analysis of Volatiles in White Wine on VOCOL® after SPME using a 75 μm Carboxen/PDMS Fiber

From our library of Articles, Sigma-Aldrich presents GC Analysis of Volatiles in White Wine on VOCOL® after SPME using a 75 μm Carboxen/PDMS Fiber
Keywords: Chromatography, Gas chromatography, Gas chromatography mass spectrometry, Mass spectrometry, Purification, Solid phase microextractions

GC Analysis of a 12-Component Esters and Ethers Mix on SLB®-IL60, Comparison to a Polyethylene Glycol (PEG) Column

From our library of Articles, Sigma-Aldrich presents GC Analysis of a 12-Component Esters and Ethers Mix on SLB®-IL60, Comparison to a Polyethylene Glycol (PEG) Column
Keywords: Chromatography, Flame ionization detector, Gas chromatography

GC Analysis of a 56-Component Industrial Solvents Mix on SLB®-IL60, Comparison to a Polyethylene Glycol (PEG) Column

From our library of Articles, Sigma-Aldrich presents GC Analysis of a 56-Component Industrial Solvents Mix on SLB®-IL60, Comparison to a Polyethylene Glycol (PEG) Column
Keywords: Chromatography, Flame ionization detector, Gas chromatography

GC Analysis of an Indoor Air Standard on Equity®-1

From our library of Articles, Sigma-Aldrich presents GC Analysis of an Indoor Air Standard on Equity®-1
Keywords: Air Monitoring, Chromatography, Gas chromatography, Purification, Size-exclusion chromatography

US EPA Method TO-17: GC Analysis of Volatiles on Equity®-1 after Collection/Desorption using Carbotrap 300 Tube

From our library of Articles, Sigma-Aldrich presents US EPA Method TO-17: GC Analysis of Volatiles on Equity®-1 after Collection/Desorption using Carbotrap 300 Tube
Keywords: Chromatography, Gas chromatography

Peer-Reviewed Papers
15

References

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