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Glyceryl Monooleate

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: Glycerol mono-oleate

  • CAS Number 25496-72-4

  • Empirical Formula (Hill Notation) C21H40O4

  • Molecular Weight 356.54

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, Chinese Food Contact Materials Regulation GB 9685 2016, E-J, Food & Beverage Standards,
Quality Level   300
grade   certified reference material
  pharmaceutical secondary standard
packaging   pkg of 1 g
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
Featured Industry   Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to USP 1295753
InChI   1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-
InChI key   RZRNAYUHWVFMIP-KTKRTIGZSA-N

Description

General description

Glyceryl Monooleate, commonly known as monoolein, is a glycerol monoester of oleic acid. Pharmaceutically, it is used as an emulsifier and permeation enhancer.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Glyceryl Monooleate may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by high performance liquid chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA3032 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

ASTM D6584: GC Analysis of Glycerin Impurity in B100 Biodiesel on MET-Biodiesel

From our library of Articles, Sigma-Aldrich presents ASTM D6584: GC Analysis of Glycerin Impurity in B100 Biodiesel on MET-Biodiesel
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification

Peer-Reviewed Papers
15

References

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