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PHR1490 Supelco

Monoethanolamine

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: 2-Aminoethanol, 2-Aminoethyl alcohol, ETA, Ethanolamine, MEA 90, MEA-LCI, MEA, Monoethanolamine

  • CAS Number 141-43-5

  • Linear Formula NH2CH2CH2OH

  • Molecular Weight 61.08

  •  Beilstein/REAXYS Number 505944

  •  EC Number 205-483-3

  •  MDL number MFCD00008183

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, Chinese Food Contact Materials Regulation GB 9685 2016, Food & Beverage Standards, Food Contact Materials,
Quality Level   300
grade   certified reference material
  pharmaceutical secondary standard
vapor density   2.1 (vs air)
vapor pressure   0.2 mmHg ( 20 °C)
description   Pharmaceutical Secondary Standard; Certified Reference Material
autoignition temp.   1436 °F
expl. lim.   17 %
packaging   pkg of 1 mL
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
refractive index   n20/D 1.454 (lit.)
bp   170 °C (lit.)
  69-70 °C/10 mmHg
mp   10-11 °C (lit.)
density   1.012 g/mL at 25 °C (lit.)
Featured Industry   Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to PhEur Y0001184
  traceable to USP 1445925
SMILES string   NCCO
InChI   1S/C2H7NO/c3-1-2-4/h4H,1-3H2
InChI key   HZAXFHJVJLSVMW-UHFFFAOYSA-N

Description

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Monoethanolamine is majorly used in pharmaceutical formulations in the buffer systems, and emulsion preparations. It can also be used as a solvent for fats and oils and to synthesize many salts having therapeutic essence.

Application

Monoethanolamine may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations and cosmetic products by chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC2076 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Target organs 
Respiratory system
RIDADR 
UN 2491 8 / PGIII
WGK Germany 
WGK 1
Flash Point(F) 
195.8 °F - Pensky-Martens closed cup
Flash Point(C) 
91 °C - Pensky-Martens closed cup
Protocols & Articles
Peer-Reviewed Papers
15

References

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