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PHR1541 Supelco

Leucovorin Calcium

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: Calcium folinate, Folinic acid calcium salt

  • CAS Number 1492-18-8

  • Empirical Formula (Hill Notation) C20H21CaN7O7

  • Molecular Weight 511.50

  •  EC Number 216-082-8

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Properties

Related Categories Additional Standards, Analytical Standards, Analytical/Chromatography, Chromatography, I-Z,
grade   certified reference material
  pharmaceutical secondary standard
packaging   ampule of 1 g
Featured Industry   Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to BP 923
  traceable to PhEur C0250000
  traceable to USP 1358004

Description

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Leucovorin Calcium may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography (HPLC).

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC1687 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
2

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles

Articles

HPLC Analysis of Folinic Acid Enantiomers on Astec® CHIROBIOTIC® T (RP mode)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Folinic Acid Enantiomers on Astec® CHIROBIOTIC® T (RP mode)
Keywords: Antitumor agents, Chromatography, High performance liquid chromatography, Pharmaceutical, Vitamins

HPLC Analysis of Folinic Acid Enantiomers on Astec® CHIROBIOTIC® T

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Folinic Acid Enantiomers on Astec® CHIROBIOTIC® T
Keywords: Antitumor agents, Chromatography, High performance liquid chromatography, Pharmaceutical, Vitamins

Peer-Reviewed Papers
15

References

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