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PHR1558 Supelco

Pyridine

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: Pyridine

  • CAS Number 110-86-1

  • Empirical Formula (Hill Notation) C5H5N

  • Molecular Weight 79.10

  •  Beilstein/REAXYS Number 103233

  •  EC Number 203-809-9

  •  MDL number MFCD00011732

  •  PubChem Substance ID 329823467

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, P-S, Pharmaceutical Secondary Standards, Pharmacopeia & Metrological Institutes Standards More...
grade   certified reference material
  pharmaceutical secondary standard
vapor density   2.72 (vs air)
vapor pressure   10 mmHg ( 13.2 °C)
  20 mmHg ( 25 °C)
InChI Key   JUJWROOIHBZHMG-UHFFFAOYSA-N
autoignition temp.   899 °F
expl. lim.   12.4 %
packaging   ampule of 3x1.2 mL each
refractive index   n20/D 1.509 (lit.)
bp   115 °C (lit.)
mp   −42 °C (lit.)
density   0.978 g/mL at 25 °C (lit.)
Featured Industry   Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to USP 1601747

Description

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Pyridine is a heterocyclic aromatic compound that is a commonly used solvent in organic and inorganic chemistry. Its weakly basic nature allows it to act as a proton acceptor in acid base reactions, and to form salts with strong acids. In the acylation of alcohols, pyridine can act as a nucleophilic catalyst.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAC0263 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN1282 - class 3 - PG 2 - Pyridine
WGK Germany 
2
Flash Point(F) 
62.6 °F
Flash Point(C) 
17 °C
Protocols & Articles

Articles

GC Analysis of Class 2 Residual Solvents on Equity®-1 after SPME using 85 μm Polyacrylate Fiber

From our library of Articles, Sigma-Aldrich presents GC Analysis of Class 2 Residual Solvents on Equity®-1 after SPME using 85 μm Polyacrylate Fiber
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Pharmaceutical, Size-exclusion chromatography, Solid phase microextractions

GC Analysis of Class 2 Residual Solvents on OVI-G43

From our library of Articles, Sigma-Aldrich presents GC Analysis of Class 2 Residual Solvents on OVI-G43
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Pharmaceutical, Size-exclusion chromatography

GC Analysis of Class 2 Residual Solvents on VOCOL® after SPME using 85 μm Polyacrylate Fiber

From our library of Articles, Sigma-Aldrich presents GC Analysis of Class 2 Residual Solvents on VOCOL® after SPME using 85 μm Polyacrylate Fiber
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Pharmaceutical, Size-exclusion chromatography, Solid phase microextractions

GC Analysis of Volatiles in Roasted Coffee Beans on Omegawax® after SPME using a 50/30 μm DVB/Carboxen/PDMS Fiber

From our library of Articles, Sigma-Aldrich presents GC Analysis of Volatiles in Roasted Coffee Beans on Omegawax® after SPME using a 50/30 μm DVB/Carboxen/PDMS Fiber
Keywords: Chromatography, Gas chromatography, Mass spectrometry, Purification, Size-exclusion chromatography, Solid phase microextractions

US EPA Method 8270 (Appendix IX): GC Analysis of Semivolatiles on Equity®-5 (30 m x 0.25 mm I.D., 0.50 μm)

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270 (Appendix IX): GC Analysis of Semivolatiles on Equity®-5 (30 m x 0.25 mm I.D., 0.50 μm)
Keywords: Chromatography, Gas chromatography, Mass selective detector, Purification

US EPA Method 8270 (Appendix IX): GC Analysis of Semivolatiles on SLB®-5ms (30 m x 0.25 mm I.D., 0.50 μm)

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270 (Appendix IX): GC Analysis of Semivolatiles on SLB®-5ms (30 m x 0.25 mm I.D., 0.50 μm)
Keywords: Chromatography, Gas chromatography, Purification

US EPA Method 8270: GC Analysis of Semivolatiles on Equity®-5

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on Equity®-5
Keywords: Chromatography, Gas chromatography, Mass selective detector, Purification

US EPA Method 8270: GC Analysis of Semivolatiles on SLB-5ms (20 m x 0.18 mm I.D., 0.36 μm), Fast GC Analysis

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on SLB-5ms (20 m x 0.18 mm I.D., 0.36 μm), Fast GC Analysis
Keywords: Chromatography, Gas chromatography, Purification

US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms (20 m x 0.18 mm I.D., 0.18 μm), Fast GC Analysis

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms (20 m x 0.18 mm I.D., 0.18 μm), Fast GC Analysis
Keywords: Chromatography, Gas chromatography, Purification, Size-exclusion chromatography

US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms (20 m x 0.18 mm I.D., 0.36 μm), 28 °C/min Oven Ramp, Fast GC Analysis

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms (20 m x 0.18 mm I.D., 0.36 μm), 28 °C/min Oven Ramp, Fast GC Analysis
Keywords: Chromatography, Gas chromatography, Purification

US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms (30 m x 0.25 mm I.D., 0.50 μm)

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms (30 m x 0.25 mm I.D., 0.50 μm)
Keywords: Chromatography, Gas chromatography, Purification

US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms, 350 °C Final Oven Temp.

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms, 350 °C Final Oven Temp.
Keywords: Chromatography, Gas chromatography

US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms

From our library of Articles, Sigma-Aldrich presents US EPA Method 8270: GC Analysis of Semivolatiles on SLB®-5ms
Keywords: Chromatography, Gas chromatography, Purification

Peer-Reviewed Papers
15

References

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