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PHR1569 Supelco

Levocarnitine

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: (−)-(R)-3-Hydroxy-4-(trimethylammonio)butyrate, L-Carnitine inner salt, Vitamin BT

  • CAS Number 541-15-1

  • Linear Formula (CH3)3N+CH2CH(OH)CH2COO-

  • Molecular Weight 161.20

  •  Beilstein/REAXYS Number 4292315

  •  EC Number 208-768-0

  •  MDL number MFCD00038747

  •  PubChem Substance ID 329823478

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, K-O, Pharmaceutical Secondary Standards, Pharmacopeia & Metrological Institutes Standards More...
grade   certified reference material
  pharmaceutical secondary standard
InChI Key   PHIQHXFUZVPYII-ZCFIWIBFSA-N
packaging   pkg of 1 g
mp   197-212 °C (lit.)
Featured Industry   Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to PhEur L0399900
  traceable to USP 1359903

Description

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Levocarnitine is a naturally available compound that plays a significant role in fatty acid oxidation and energy production in the human body. It is majorly found in skeletal and cardiac muscles of mammals and facilitates the transport of long chain fatty acids into mitochondria.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Carnitine is a quaternary amine that occurs naturally in most mammalian tissue. It is present in relatively high concentrations in skeletal muscle and heart where it is involved in regulating energy metabolism. It shifts glucose metabolism from glycolysis to glycogen storage and enhances the transport of long chain fatty acids into the mitochondria where they are oxidized for energy production.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAB7787 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles
Peer-Reviewed Papers
15

References

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