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PHR1581 Supelco

Uracil

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: 2,4(1H,3H)-Pyrimidinedione, 2,4-Dihydroxypyrimidine, 2,4-Pyrimidinediol, Uracil

  • CAS Number 66-22-8

  • Empirical Formula (Hill Notation) C4H4N2O2

  • Molecular Weight 112.09

  •  Beilstein/REAXYS Number 507828

  •  EC Number 200-621-9

  •  MDL number MFCD00006016

  •  PubChem Substance ID 329823489

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, Pharmaceutical Secondary Standards, Pharmacopeia & Metrological Institutes Standards, T-Z More...
Quality Level   300
grade   certified reference material
  pharmaceutical secondary standard
packaging   pkg of 100 mg
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
mp   >300 °C (lit.)
Featured Industry   Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to PhEur Y0000764
  traceable to USP 1705753
SMILES string   O=C1NC=CC(=O)N1
InChI   1S/C4H4N2O2/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8)
InChI key   ISAKRJDGNUQOIC-UHFFFAOYSA-N

Description

General description

Certified pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Uracil is one of the nucleotide bases of RNA. It is the precursor of DNA′s thymine. It acts like a carrier of genetic data and is hooked up with a ribose and three phosphates to form a ribonucleoside triphosphate once a human body produces nucleotides.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA4497 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles

Articles

HPLC Analysis of Column Test Mixture on Ascentis® Express RP-Amide

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Column Test Mixture on Ascentis® Express RP-Amide
Keywords: High performance liquid chromatography

HPLC Analysis of Four Proteins on Zenix® SEC-300, Comparison of Column Internal Diameter

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Four Proteins on Zenix® SEC-300, Comparison of Column Internal Diameter
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of Hydrophobic Bases on Ascentis® RP-Amide

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Hydrophobic Bases on Ascentis® RP-Amide
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of Nucleic Acid Bases on Ascentis® Si

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Nucleic Acid Bases on Ascentis® Si
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of Nucleobases using TSKgel® SuperSW mAb HTP column in HILIC mode

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Nucleobases using TSKgel® SuperSW mAb HTP column in HILIC mode
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of Polar and Non-Polar Analytes on Ascentis® Express C18, Column Test Mixture

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Polar and Non-Polar Analytes on Ascentis® Express C18, Column Test Mixture
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Polar and Non-Polar Analytes on Ascentis® Express C8, Column Test Mixture

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Polar and Non-Polar Analytes on Ascentis® Express C8, Column Test Mixture
Keywords: Chromatography, High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Protein Standards by Size Exclusion on Zenix® as Affected by Pore Size: 100Å vs. 300Å

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Protein Standards by Size Exclusion on Zenix® as Affected by Pore Size: 100Å vs. 300Å
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of Protein Standards on Zenix® SEC-300 at Low Flow Rate

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Protein Standards on Zenix® SEC-300 at Low Flow Rate
Keywords: Chromatography, Diffusion, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of Protein Standards on Zenix® SEC-300 by Size Exclusion As Affected by Arginine

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Protein Standards on Zenix® SEC-300 by Size Exclusion As Affected by Arginine
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of Protein Standards on Zenix® SEC-300 by Size Exclusion As Affected by Potassium Chloride

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Protein Standards on Zenix® SEC-300 by Size Exclusion As Affected by Potassium Chloride
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of Protein Standards on Zenix® SEC-300 by Size Exclusion As Affected by Sodium Perchlorate

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Protein Standards on Zenix® SEC-300 by Size Exclusion As Affected by Sodium Perchlorate
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of Protein Standards on Zenix® SEC-300 in the Presence of a Denaturant

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Protein Standards on Zenix® SEC-300 in the Presence of a Denaturant
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of Protein Standards on Zenix® SEC-300 using Different Buffer Systems

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Protein Standards on Zenix® SEC-300 using Different Buffer Systems
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of Proteins by Size Exclusion on Zenix® Columns, Effect of Pore Size

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Proteins by Size Exclusion on Zenix® Columns, Effect of Pore Size
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of Proteins by Size Exclusion on Zenix® SEC-300 Columns, Effect of Flow Rate (15 cm column)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Proteins by Size Exclusion on Zenix® SEC-300 Columns, Effect of Flow Rate (15 cm column)
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of Proteins by Size Exclusion on Zenix® SEC-300 Columns, Effect of Flow Rate (30 cm column)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Proteins by Size Exclusion on Zenix® SEC-300 Columns, Effect of Flow Rate (30 cm column)
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of Proteins by Size Exclusion on Zenix® and SRT® SEC-300, Comparison of Particle Size and Column I.D.

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Proteins by Size Exclusion on Zenix® and SRT® SEC-300, Comparison of Particle Size and Column I.D.
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

HPLC Analysis of Purines and Pyrimidines of Nucleic Acids on Ascentis® Si (Silica)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Purines and Pyrimidines of Nucleic Acids on Ascentis® Si (Silica)
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of Substituted Aromatic Compounds on Ascentis® Express Biphenyl

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Substituted Aromatic Compounds on Ascentis® Express Biphenyl
Keywords: Chromatography, High performance liquid chromatography, Separation

HPLC Analysis of Thyroglobulin, gamma-Globulins, Ovalbumin, Myoglobin, and Poly-DL-Alanine on Zenix® SEC-150, 30 cm x 7.8 mm I.D., 3 μm particles

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Thyroglobulin, gamma-Globulins, Ovalbumin, Myoglobin, and Poly-DL-Alanine on Zenix® SEC-150, 30 cm x 7.8 mm I.D., 3 μm particles
Keywords: Antibiotics, Antimicrobials, Chromatography, Clinical, High performance liquid chromatography, Separation, Size-exclusion chromatography

Protein Molecular Weight Calibration Curve on Zenix® Size Exclusion Columns, Effect of Pore Size

From our library of Articles, Sigma-Aldrich presents Protein Molecular Weight Calibration Curve on Zenix® Size Exclusion Columns, Effect of Pore Size
Keywords: Chromatography, High performance liquid chromatography, Size-exclusion chromatography

UHPLC Analysis of Barbiturates on Titan™ C18

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of Barbiturates on Titan™ C18
Keywords: Anti-depressants, Anticonvulsants, Chromatography, Clinical, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Pharmaceutical, Solvents

UHPLC Analysis of Diazepam and Metabolites on Titan™ C18, Competitive Comparison

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis of Diazepam and Metabolites on Titan™ C18, Competitive Comparison
Keywords: Anti-depressants, Anticonvulsants, Chromatography, Clinical, Mass spectrometry, Metabolites, Pharmaceutical

Peer-Reviewed Papers
15

References

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