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PHR1586 Supelco

Oleic Acid

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: cis-9-Octadecenoic acid, Elainic acid, Oleic acid

  • CAS Number 112-80-1

  • Linear Formula CH3(CH2)7CH=CH(CH2)7COOH

  • Molecular Weight 282.46

  •  Beilstein/REAXYS Number 1726542

  •  EC Number 204-007-1

  •  MDL number MFCD00064242

  •  PubChem Substance ID 329823492

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, Extractables and Leachables, Food & Beverage Standards, Food and Cosmetic Component Standards,
grade   certified reference material
  pharmaceutical secondary standard
vapor pressure   1 mmHg ( 176 °C)
InChI Key   ZQPPMHVWECSIRJ-KTKRTIGZSA-N
packaging   pkg of 1 g
refractive index   n20/D 1.459 (lit.)
bp   194-195 °C/1.2 mmHg (lit.)
mp   13-14 °C (lit.)
density   0.89 g/mL at 25 °C (lit.)
Featured Industry   Pharmaceutical (small molecule)
format   neat
pharmacopeia traceability   traceable to PhEur Y0001479
  traceable to USP 1478130

Description

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Oleic Acid may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem/physiol Actions

Activates protein kinase C in hepatocytes.

Uncouples oxidative phosphorylation. Inhibits 2,4-dinitrophenol−stimulated ATPase. Action reversed by adding serum albumin.

Analysis Note

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Footnote

To see an example of a Certificate of Analysis for this material enter LRAA4565 in the slot below. This is an example certificate only and may not be the lot that you receive.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1
Flash Point(F) 
>235.4 °F
Flash Point(C) 
>113 °C
Protocols & Articles

Articles

HPLC Analysis of Fatty Acids on Ascentis® RP-Amide

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Fatty Acids on Ascentis® RP-Amide
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of Free Fatty Acids on SUPELCOSIL™ LC-8

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Free Fatty Acids on SUPELCOSIL™ LC-8
Keywords: Chromatography, High performance liquid chromatography

Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

Y0001479 Oleic acid, European Pharmacopoeia (EP) Reference Standard
1478130 Oleic acid, United States Pharmacopeia (USP) Reference Standard

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